Nucl Med Mol Imaging.  2021 Dec;55(6):323-324. 10.1007/s13139-021-00718-2.

Increased 68 Ga-PSMA-11 Bone Marrow and Splenic Uptake in a Case of Erythroid Myelodysplasia

• Donegani M
• Raffa S
• Miceli A
• Morbelli S
• Bauckneht M

• KMID: 2523589
• DOI: http://doi.org/10.1007/s13139-021-00718-2

Abstract

We describe the case of an 82-year-old man who underwent ⁶⁸  Ga-prostate-specific membrane antigen-11 ( ⁶⁸  Ga-PSMA-11) positron emission tomography/computed tomography (PET/CT) for the restaging of prostate carcinoma. ⁶⁸  Ga-PSMA-11 PET/CT unexpectedly showed increased tracer uptake homogenously involving the axial and appendicular bone marrow and the spleen, not characteristic for metastatic prostate disease. Further investigations revealed that 2 months before the patient underwent bone marrow biopsy, which showed the occurrence of monolinear myelodysplasia.

Keyword

Myelodysplasia; Prostate-specific membrane antigen; PET/CT