Nucl Med Mol Imaging.  2021 Dec;55(6):323-324. 10.1007/s13139-021-00718-2.

Increased 68 Ga-PSMA-11 Bone Marrow and Splenic Uptake in a Case of Erythroid Myelodysplasia

Affiliations
  • 1Department of Health Sciences (DISSAL), University of Genova, Genova, Italy
  • 2Nuclear Medicine, IRCCS Ospedale Policlinico San Martino, Genova, Italy

Abstract

We describe the case of an 82-year-old man who underwent 68  Ga-prostate-specific membrane antigen-11 ( 68  Ga-PSMA-11) positron emission tomography/computed tomography (PET/CT) for the restaging of prostate carcinoma. 68  Ga-PSMA-11 PET/CT unexpectedly showed increased tracer uptake homogenously involving the axial and appendicular bone marrow and the spleen, not characteristic for metastatic prostate disease. Further investigations revealed that 2 months before the patient underwent bone marrow biopsy, which showed the occurrence of monolinear myelodysplasia.

Keyword

Myelodysplasia; Prostate-specific membrane antigen; PET/CT
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