J Chest Surg.  2021 Dec;54(6):528-531. 10.5090/jcs.21.016.

Huge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review

• Lee HS
• Kim J
• Moon DH
• Park CH
• Jeon TJ
• Lee S
• Cha YJ

• KMID: 2523189
• DOI: http://doi.org/10.5090/jcs.21.016

Abstract

Pulmonary sclerosing pneumocytoma (PSP) is a tumor of pneumocytic origin that is classified as a benign neoplasm. To date, aggressive behavior of this tumor has rarely been reported. Here, we describe a case of a 56-year-old woman with a huge, 19-cm PSP that resulted in mediastinal shift and showed microscopic endobronchial invasion and necrosis. The differential diagnosis included malignant mesenchymal tumors, such as solitary fibrous tumor; however, PSP was confirmed based on the characteristic thyroid transcription factor 1 positivity and membranous expression of Ki-67 on immunohistochemical staining of tumor cells.

Keyword

Pulmonary sclerosing hemangioma; Computed tomography; Immunohistochemistry; Case report