Osong Public Health Res Perspect.  2012 Mar;3(1):48-59. 10.1016/j.phrp.2012.02.002.

In vivo Noninvasive Small Animal Molecular Imaging

• Youn H
• Hong KJ

• KMID: 2518311
• DOI: http://doi.org/10.1016/j.phrp.2012.02.002

Abstract

The remarkable efforts that are made on molecular imaging technologies demonstrate its potential importance and range of applications. The generation of disease-specific animal models, and the developments of target-specific probes and genetically encoded reporters are another important component. Continued improvements in the instrumentation, the identification of novel targets and genes, and the availability of improved imaging probes should be made. Multimodal imaging probes should provide easier transitions between laboratory studies, including small animal studies and clinical applications. Here, we reviewed basic strategies of noninvasive in vivo imaging methods in small animals to introducing the concept of molecular imaging.

Keyword

animal imaging; computed tomography; magnetic resonance imaging; nuclear imaging; optical imaging; ultrasonography