Ann Dermatol.
2021 Jun;33(3):271-274. 10.5021/ad.2021.33.3.271.
A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP
- Affiliations
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- 1Departments of Dermatology, Seoul National University Bundang Hospital, Seongnam, Korea
- 2Departments of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
- 3Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea
- KMID: 2515746
- DOI: http://doi.org/10.5021/ad.2021.33.3.271
Abstract
- Paraneoplastic pemphigus is a rare, life-threatening disorder associated with an underlying neoplasm, which presents with painful stomatitis and polymorphous skin lesions. Successful diagnosis of paraneoplastic pemphigus can lead to the diagnosis and treatment of the underlying malignancy.However, involvement of the respiratory system is typically unresponsive to treatment. Herein, we report the case of a 44-year-old female diagnosed with paraneoplastic pemphigus with underlying follicular lymphoma treated with a chemotherapy regimen including rituximab. Her skin lesions and underlying lymphoma responded to treatment, but bronchiolitis obliterans continued to progress and resulted in fatal respiratory failure.
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