J Korean Neurol Assoc.
2022 Oct;40(4):331-333. 10.17340/jkna.2022.4.9.
MOG Antibody-Positive Myelopathy as a Paraneoplastic Manifestation of Lymphoma
- Affiliations
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- 1Department of Neurology, Catholic University of Daegu School of Medicine, Daegu, Korea
- KMID: 2535875
- DOI: http://doi.org/10.17340/jkna.2022.4.9
Abstract
- Although myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an autoimmune demyelinating disease, it may occur as a paraneoplastic syndrome in rare instances. A 80-year-old woman presented with paresthesia and weakness of four extremities for 10 days. Spine magnetic resonance imaging showed longitudinally extensive transverse myelitis. Laboratory tests revealed positive MOG antibodies. Both high-dose intravenous methylprednisolone and plasma exchange were not effective and further evaluation showed lymphoma. Herein, we reported a case of MOG-positive paraneoplastic myelopathy with lymphoma.
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