Nat Prod Sci.
2021 Mar;27(1):45-48. 10.20307/nps.2021.27.1.45.
Macasiamenene V, a New Stilbenoid from the Leaves of Macaranga inermis
- Affiliations
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- 1Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya, Indonesia
- KMID: 2514909
- DOI: http://doi.org/10.20307/nps.2021.27.1.45
Abstract
- One new compound, macasiamenene V (1), and two known stilbenes (2 - 3) were isolated from Macaranga inermis Pax & K.Hoffm leaves. The structure of 1 was fully assigned based on the information on high-resolution MS and (1D, 2D) NMR spectra. The cytotoxic of compounds 1 - 3 was evaluated against 4T1 and HeLa cells. Compounds 2 - 3 showed high activity against HeLa cells with an IC 50 value of 1.09 and 0.88 μg/mL, respectively.
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