Int J Oral Biol.
2021 Mar;46(1):45-50. 10.11620/IJOB.2021.46.1.45.
The antibacterial effect of Endoseal TCS mixed with water-soluble mangostin derivatives of Garcinia mangostana L. ethanol extract against Enterococcus faecalis and Staphylococcus aureus
- Affiliations
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- 1Department of Conservative Dentistry, Chosun University, Gwangju 61452, Republic of Korea
- 2Korean Collection for Oral Microbiology, Chosun University, Gwangju 61452, Republic of Korea
- 3Department of Oral Biochemistry, School of Dentistry, Chosun University, Gwangju 61452, Republic of Korea
- 4Medi Bio Lab Co., Ltd., Seoul 61452, Republic of Korea
- KMID: 2514829
- DOI: http://doi.org/10.11620/IJOB.2021.46.1.45
Abstract
- This study evaluated the antimicrobial activity of Endoseal TCS, an mineral trioxide aggregate-based root canal sealer, mixed with water-soluble mangostin derivatives (WsMD) of Garcinia mangostana L. (mangosteen) ethanol extract against Enterococcus faecalis and Staphylococcus aureus. The antibacterial activity of Endoseal TCS mixed with WsMD against three strains of E. faecalis and three strains of S. aureus was performed using agar diffusion test. The data showed that Endoseal TCS mixed with 0.115% WsMD had a zone of inhibition of 0.7 ± 0.2–2.4 ± 0.1 mm. The results suggest that Endoseal TCS mixed with WsMD of Garcinia mangostana L. ethanol extract is useful as a root canal sealer with antibacterial activity against E. faecalis and S. aureus.
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