Korean J Gastroenterol.  2020 Jul;76(1):46-48. 10.4166/kjg.2020.76.1.46.

Pancreatic Hemangioma Suspected of Neuroendocrine Tumor

• Jeong MA
• Lee JK
• Nam JH
• Jang DK
• Lim YJ
• Lee JJ
• Kim EJ

• KMID: 2504594
• DOI: http://doi.org/10.4166/kjg.2020.76.1.46

Abstract

Adult pancreatic hemangioma is an extremely rare disease, with only 22 cases reported since 1939. Pancreatic hemangioma has no specific symptoms, diagnostic imaging, or laboratory findings, making it difficult to be clinically suspected and diagnosed. The majority are confirmed after surgery. In this report, a 61-year-old woman presented with melena and showed multiple small hyper- vascular lesions in the pancreas. A pancreatic neuroendocrine tumor was suspected, and the patient underwent a distal pancreatectomy. The pathology examination and immunohistochemical study revealed a pancreatic hemangioma.

Keyword

Hemangioma; Neuroendocrine tumors; Pancreas

Figure

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  Fig. 1 Contrast-enhanced computed tomography scan during the arterial phase shows multiple hypervascular lesions in the pancreas (arrows), and the largest lesion was 14 mm in the uncinate process.

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  Fig. 2 Magnetic resonance imaging after gadolinium enhancement during the arterial phase shows multiple hyperintense lesions in the pancreas (arrows).

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  Fig. 3 Gross specimen shows two well-demarcated multilocular cystic lesions (arrows).

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  Fig. 4 Microscopic findings. (A) Hematoxylin and eosin stain of the tumor showing large dilated vessels lined by flattened endothelium (×100) and (B) immunohistochemical stain for CD34 is positive (×40).

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