Korean J Clin Oncol.  2020 Jun;16(1):25-32. 10.14216/kjco.20005.

Poorly differentiated thyroid carcinoma: An institutional experience

Affiliations
  • 1Department of Surgery, Gachon University Gil Medical Center, Incheon, Korea
  • 2Department of Surgery, Gachon University College of Medicine, Incheon, Korea
  • 3Department of Pathology, Gachon University College of Medicine, Incheon, Korea

Abstract

Purpose
The incidence of poorly differentiated thyroid carcinoma (PDTC) is extremely low among thyroid cancers and there is no standardized treatment guideline for it. In this study, we have analyzed PDTC patients and reviewed their clinicopathological features.
Methods
Data of PDTC patients from our institution are collected through the electronic medical database. We analyzed them by several parameters such as basic demographics, presenting symptom, preoperative cytology results, associated pathology, surgical results, surgery type, and distant metastasis.
Results
We collected 23 cases in our institution. Apart from two patients who were transferred to another hospital upon diagnosis, all 21 operated cases are analyzed. The parameters we studied were age, sex, presenting symptoms, distant metastasis and pathological features such as tumor size, associated pathology, predominant pattern and so on. We also provided descriptive analyses according to the type of presentation and treatment; patients with distant metastasis, juvenile cancer, and concurrent hyperthyroidism. Furthermore, we provided different cases in which the initial surgical plans differed.
Conclusion
We present 21 cases of PDTC patients and clarify their clinicopathological features. Despite some limitations, this study may shed light for future research regarding treatment of PDTC patients.

Keyword

Thyroid neoplasms; Neoplasm metastasis; Surgery
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