Korean J Blood Transfus.  2020 Apr;31(1):67-69. 10.17945/kjbt.2020.31.1.67.

Practical Considerations in Convalescent Plasma Therapy for Coronavirus Disease 2019

  • 1Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea
  • 2Division of Human Blood Safety Surveillance, Korea Centers for Disease Control and Prevention, Cheongju, Korea


Convalescent plasma therapy has been used to achieve passive immunization against diverse infectious agents by administering pathogen-specific antibodies. Coronavirus disease 19 (COVID-19), which originated in Wuhan, China, has recently become a major concern all over the world. There are no specific treatment recommendations for COVID-19 because of the lack of knowledge and evidence about this virus. Convalescent plasma therapy can be used as an empirical and investigational treatment for COVID-19, and so we briefly describe the main issues related to convalescent plasma therapy from the perspective of transfusion medicine.


Convalescent plasma; COVID-19; Passive immunization
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