J Korean Med Sci.  2020 Apr;35(14):e149. 10.3346/jkms.2020.35.e149.

Use of Convalescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea

Affiliations
  • 1Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.
  • 4Department of Internal Medicine, National Medical Center, Seoul, Korea.

Abstract

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 not yet has established its treatment, but convalescent plasma has been expected to increase survival rates as in the case with other emerging viral infections. We describe two cases of COVID-19 treated with convalescent plasma infusion. Both patients presented severe pneumonia with acute respiratory distress syndrome and showed a favorable outcome after the use of convalescent plasma in addition to systemic corticosteroid. To our knowledge, this is the first report of the use of convalescent plasma therapy for COVID-19 in Korea.

Keyword

Coronavirus; SARS-CoV-2; COVID-19; Treatment; Convalescent Plasma
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