J Menopausal Med.
2020 Apr;26(1):39-43. 10.6118/jmm.19012.
Ovarian Stromal Hyperplasia: A Rare Cause of Postmenopausal Hyperandrogenism
- Affiliations
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- 1Department of Obstetrics and Gynecology, Manises Hospital, Valencia, Spain
- 2Department of Obstetrics and Gynecology, La Fe University Hospital, Valencia, Spain
- 3Department of Endocrinology, Manises Hospital, Valencia, Spain
- 4Department of Anatomy, Manises Hospital, Valencia, Spain
- KMID: 2500642
- DOI: http://doi.org/10.6118/jmm.19012
Abstract
- Ovarian hyperthecosis and ovarian stromal hyperplasia (OSH) are two uncommon non-neoplastic causes of ovarian hyperandrogenism, whose etiology is still unknown. These conditions are characterized by obesity, hyperinsulinemia, acanthosis nigricans, and even virilization, mainly in postmenopausal women. Here we have reported the case of a 67-year-old patient with a diagnosis of OSH, which was resolved after bilateral laparoscopic oophorectomy. In this case report, we have discussed two different conditions posing a diagnostic challenge and requiring a high index of suspicion.
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