Korean J Radiol.
2020 Apr;21(5):545-549. 10.3348/kjr.2020.0240.
Small Solitary Ground-Glass Nodule on CT as an InitialManifestation of Coronavirus Disease 2019 (COVID-19)Pneumonia
- Affiliations
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- 1Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China
- 2Department of Radiology, China Resources & WISCO General Hospital, Wuhan, China
- KMID: 2500036
- DOI: http://doi.org/10.3348/kjr.2020.0240
Abstract
- The 2019 novel coronavirus (2019-nCoV) outbreak in Wuhan, Hubei Province, China in 2019 led to large numbers of people being infected and developing atypical pneumonia (coronavirus disease 2019, COVID-19). Typical imaging manifestations of patients infected with 2019-nCoV has been reported, but we encountered an atypical radiological manifestation on baseline computed tomography (CT) images in three patients from Wuhan, China infected with the 2019-nCoV. Surprisingly, the only similar CT finding was a solitary sub-centimeter ground-glass nodule adjacent to bronchovascular bundles, which could be easily overlooked. In addition, the follow-up images in these patients showed how COVID-19 pneumonia evolved from these small nodules. The radiologic manifestation of the three cases will expand contemporary understanding of COVID-19.
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