Korean J Gastroenterol.  2020 Feb;75(2):94-97. 10.4166/kjg.2020.75.2.94.

Duodenal Leiomyosarcoma Presenting with Gastrointestinal Bleeding and Obstruction: A Case Report

Affiliations
  • 1Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
  • 2Biomedical Research Institute, Pusan National University Hospital, Busan, Korea. doc0224@pusan.ac.kr
  • 3Department of Pathology, Pusan National University School of Medicine, Busan, Korea.

Abstract

Duodenal leiomyosarcoma is a rare condition with a poor prognosis. Early diagnosis of duodenal leiomyosarcoma is challenging because it presents with nonspecific symptoms and endoscopic biopsies usually do not enable a definitive diagnosis. Duodenal leiomyosarcomas are diagnosed on the basis of the histopathological identification of a mesenchymal lesion composed of malignant tumor cells that on immunohistochemical examination is positive for smooth muscle actin and desmin. We report the case of a 38-year-old man who presented with gastrointestinal bleeding and obstruction who was diagnosed with duodenal leiomyosarcoma after surgical resection.

Keyword

Duodenal obstruction; Gastrointestinal hemorrhage; Leiomyosarcoma

MeSH Terms

Actins
Adult
Biopsy
Desmin
Diagnosis
Duodenal Obstruction
Early Diagnosis
Gastrointestinal Hemorrhage
Hemorrhage*
Humans
Leiomyosarcoma*
Muscle, Smooth
Prognosis
Actins
Desmin
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