Pediatr Emerg Med J.  2019 Dec;6(2):57-62. 10.22470/pemj.2019.00108.

Characteristics of poisoning in younger children according to different forms of the drugs

Affiliations
  • 1Department of Emergency Medicine, Ajou University School of Medicine, Suwon, Korea. eesysook@naver.com

Abstract

PURPOSE
This study aimed to investigate the characteristics of poisoning drug ingested by younger children, and to compare the clinical outcome by drug forms.
METHODS
This was a retrospective analysis based on medical records from the Emergency Department based Injury In-depth Surveillance (EDIIS) registry in Korea from January to December 2015. Patients aged 7 years or younger visiting the emergency department (ED) with drug poisoning were included. We classified the forms of drugs as tablets or syrup, and analyzed the characteristics by size, color, and shape. In addition, clinical outcomes and ED length of stay were compared according to the drug forms.
RESULTS
A total of 308 cases were collected, and 202 patients finally were analyzed. Tablets and capsules (TACs) were more common than syrup (67.3% vs. 32.7%). Regarding clinical outcomes, patients who took TACs had higher admission rate (17.6% vs. 7.6%, P = 0.040) without a significant difference in ED length of stay compared to those who took syrups. While commonly ingested drugs in TACs were hormones, sedative and analgesics, frequent drugs in syrup were antihistamines and cold drugs. In 136 case of TACs, median long and short axes were 0.85 cm (interquartile range [IQR], 0.7-1.1 cm) and 0.72 cm (IQR, 0.59-0.82 cm), respectively. Chromatic TACs were 80 cases (58.8%) and more common than achromatic TACs. Round shapes were preferred than angular ones (96.3% vs. 3.7%).
CONCLUSION
In younger children poisonings, the TACs showed higher incidence and admission rate compared to syrups. Especially, chromatic TACs and round shapes were preferred. Therefore, drugs with these characteristics need to be stored more carefully.

Keyword

Child; Dosage forms; Drug Compounding; Poisoning; Syrup; Tablets

MeSH Terms

Analgesics
Capsules
Child*
Dosage Forms
Drug Compounding
Emergency Service, Hospital
Histamine Antagonists
Humans
Incidence
Korea
Length of Stay
Medical Records
Poisoning*
Retrospective Studies
Tablets
Analgesics
Capsules
Dosage Forms
Histamine Antagonists
Tablets
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