J Korean Soc Radiol.  2020 Jan;81(1):243-247. 10.3348/jksr.2020.81.1.243.

Serial Magnetic Resonance Imaging Findings in Hyperglycemia-Related Osmotic Demyelination Syndrome: A Case Report

Affiliations
  • 1Department of Radiology, Myongji Hospital, Hanyang University College of Medicine, Goyang, Korea. nhpark@mjh.or.kr

Abstract

We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst. A few days later, he complained of dysarthria, dysphasia, and dysmetria. Laboratory examinations showed significant hyperglycemia, but normal electrolyte levels. Brain MRI revealed T2-signal abnormalities that were symmetrical, non-space occupying, and located in the central pons with a peripheral sparing pattern, which were suggestive of ODS. In addition, subsequent MRI revealed progression of signal hyperintensity; however, the patient's symptoms improved.


MeSH Terms

Aphasia
Brain
Cerebellar Ataxia
Demyelinating Diseases*
Dysarthria
Humans
Hyperglycemia
Magnetic Resonance Imaging*
Middle Aged
Pons
Thirst
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