Radiat Oncol J.  2019 Dec;37(4):232-248. 10.3857/roj.2019.00633.

Current status of proton therapy techniques for lung cancer

• Han Y

• KMID: 2468731
• DOI: http://doi.org/10.3857/roj.2019.00633

Abstract

Proton beams have been used for cancer treatment for more than 28 years, and several technological advancements have been made to achieve improved clinical outcomes by delivering more accurate and conformal doses to the target cancer cells while minimizing the dose to normal tissues. The state-of-the-art intensity modulated proton therapy is now prevailing as a major treatment technique in proton facilities worldwide, but still faces many challenges in being applied to the lung. Thus, in this article, the current status of proton therapy technique is reviewed and issues regarding the relevant uncertainty in proton therapy in the lung are summarized.

Keyword

Proton therapy; Interplay effect; Intensity modulated proton therapy; Tumor motion; Lung cancer

MeSH Terms

Lung Neoplasms*
Lung*
Proton Therapy*
Protons*
Uncertainty
Protons