Nat Prod Sci.  2019 Dec;25(4):354-357. 10.20307/nps.2019.25.4.354.

Two New Caffeoyl Threonate Esters from the Leaves of Toxicodendron vernicifluum

• Jang JY
• Ahn JH
• Jo YH
• Turk A
• Kang SY
• Hwang BY
• Lee MK

• KMID: 2468070
• DOI: http://doi.org/10.20307/nps.2019.25.4.354

Abstract

Toxicodendron vernicifluum, also called as Rhus verniciflua is a deciduous tree belonging to Anacardiaceae family. Two new caffeoyl threonate esters, rhuseols A (1) and B (2), together with 5-O-(E)-caffeoylquinic acid methyl ester (3) were isolated from the leaves of T. vernicifluum. The structures of isolated compounds were established by using 1D and 2D NMR in combination with HR-ESI-MS. Compounds 1 - 3 showed DPPH radical scavenging effects with ICâ‚…â‚€ values of 47.9, 107.8 and 15.4 µM, respectively. Taken together, these compounds might contribute to the antioxidant properties of the leaves of T. vernicifluum, which will be useful for various oxidative stress mediated diseases.

Keyword

Toxicodendron vernicifluum; caffeoyl threonate esters; antioxidant effect

MeSH Terms

Anacardiaceae
Antioxidants
Esters*
Humans
Oxidative Stress
Rhus
Toxicodendron*
Trees
Antioxidants
Esters

Figure

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  Fig. 1 Chemical structures of compounds 1 – 3.

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  Fig. 2 Chemical structures and key 1H-1H COSY (−) and HMBC (→) correlations of compounds 1 and 2.

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