Korean J Med.
2019 Oct;94(5):410-413. 10.3904/kjm.2019.94.5.410.
The Role of the Gut Microbiota in Obesity
- Affiliations
-
- 1Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.
- 2Digestive Disease Center and Research Institute, Soonchunhyang University College of Medicine, Bucheon, Korea.
- 3Department of Gastroenterology, Catholic Kwandong University College of Medicine, Gangneung, Korea.
- 4Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. otilia94@yuhs.ac
- KMID: 2462825
- DOI: http://doi.org/10.3904/kjm.2019.94.5.410
Abstract
- Obesity is a critical target for public health interventions worldwide. There are many causes of obesity, and the importance of the gut microbiota in its pathogenesis has recently been recognized. The composition and function of the gut microbiota play a role in obesity and metabolic disease, yet the underlying mechanisms are unclear. Advances in our understanding of the link between obesity and the gut microbiota have suggested the potential of its manipulation for treating obesity. In this review, we summarize current knowledge of the interactions between the gut microbiota and obesity as well as the therapeutic potential of its modulation.
