J Korean Orthop Assoc.
1979 Sep;14(3):357-364. 10.4055/jkoa.1979.14.3.357.
Clinical Observation of 51 Cases of Osteogenic Sarcoma
- KMID: 2460274
- DOI: http://doi.org/10.4055/jkoa.1979.14.3.357
Abstract
- Osteosarcoma is a malignant neoplasm arising from the undiferenciated fibroblastic cells of the bone, and one of the most common primary malignant tumor of the bone resulting in high mortality rate. Authors performed clinical observation on 51 cases of osteogenic sarcoma at the Department of Orthopedic Surgery, Presbyterian Hospital, Taegu, Korea during the 17 year period from Jan. 1962 to Dec. 1978. The results were obtained as follows: 1. It was most common in the age group between 11 and 30 years. 2. The sex distribution was 28 cases(55.0%) in males and 23 cases(45.0%) in females. 3. The most commonly affected site was distal femur and next proximal fibia, consisting of 23 cases(45.1%) and 19 cases(36.5%) respectively. 4. The average value of serum alkaline phosphatase in all cases was 6.7 Bodansky units, and 13.9 units was the highest value in these cases. 5. The histopathologic classification revealed the osteoblastic type in 22 cases(43.1%), fibroblastic in 19 cases(37.3%), and chondroblastic in 10 cases(19.6%). 6. Among the 51 cases of osteogenic sarcoma, 29 cases(56.9%) revealed pulmonary metastasis within 1 year of diagnosis. 7 Amoung the 32 cases of osteogenic sarcoma diagnosed before Dec. 1973, 3 cases(9.4%) survived longer than 5 years.
