Ewha Med J.  1980 Sep;3(3):101-111. 10.12771/emj.1980.3.3.101.

The Chemotherapy of Malignant Bone Tumors

Affiliations
  • 1Department of Orthopaedic Surgery, College of Medicine, Ewha Womans University, Korea.

Abstract

Experiences in the adjuvant chemotherapy with adriamycin on two cases of osteogenic sarcoma of the femur and tibia and one case of Ewing's sarcoma of the femur are presented. The two cases of the osteogenic sarcoma were treated by a combination of radical amputation and chemotherapy. One case of the Ewing's sarcoma was treated by the megavoltage radiotherapy and chemotherapy. One patient with the osteosarcoma died of late pulmonary metastasis 13 months after the diagnosis and treatment, however, this patient had discontinued hie chemotherapy in three months. And also his initial amputation was delayed four months from initial diagnosis because of his hesitation. Other two cases of osteogenic and Ewing's sarcoma are carrying on normal active daily life without local recurrance or pulmonary metastasis 11-17 months after the diagnosis of the osteogenic and Ewing's sarcoma respectively. The observation and follow up period of our cases are too short to permit definite conclusions. However, preliminary results and the review of the literatures strongly support the possibility that adjuvant chemotherapy has improved the prognosis of the patients with the malignant bone tumors.


MeSH Terms

Amputation
Chemotherapy, Adjuvant
Diagnosis
Doxorubicin
Drug Therapy*
Femur
Follow-Up Studies
Humans
Neoplasm Metastasis
Osteosarcoma
Prognosis
Radiotherapy
Sarcoma, Ewing
Tibia
Doxorubicin
Full Text Links
  • EMJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr