J Korean Neurol Assoc.  2019 Aug;37(3):235-250. 10.17340/jkna.2019.3.1.

Pharmacotherapy of Diabetes Focused on Stroke

Affiliations
  • 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Chosun University Hospital, Chosun University School of Medicine, Gwangju, Korea. diabetes@chosun.ac.kr

Abstract

Cardiovascular disease, including stroke, is one of the major causes of death in diabetes. Numerous studies have long suggested reducing macrovascular complication such as ischemic vascular disease through intensive glycemic control, but none was successful proving the effect of glycemic control. Recently, new possibilities in cardiovascular disease reduction have been proposed through cardiovascular safety trials of newly developed anti-hyperglycemic agents. The purpose of this review is to introduce the traditional and newly developed anti-diabetic medications and review their effects regarding cardiovascular outcomes mainly focusing on stroke.

Keyword

Diabetes mellitus; Stroke; Diabetes complications; Hypoglycemic agents

MeSH Terms

Cardiovascular Diseases
Cause of Death
Diabetes Complications
Diabetes Mellitus
Drug Therapy*
Hypoglycemic Agents
Stroke*
Vascular Diseases
Hypoglycemic Agents
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