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Young-onset type 2 diabetes in South Korea: a review of the current status and unmet need

Yang YS, Han K, Sohn TS, Kim NH

The prevalence of young-onset (diagnosis at age < 40 years) type 2 diabetes mellitus (T2DM) is increasing globally. Young-onset T2DM has a common pathophysiology of glucose dysregulation as in late-onset...
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Type 2 Diabetes Mellitus Increases Peritonsillar Abscess Susceptibility: Real-World Evidence

Wu CL, Tsai MS, Lee TJ, Wang YT, Liu CY, Yang YH, Tsai YT, Hsu CM, Wu CY, Chang PJ, Chang GH

Objectives. Type 2 diabetes mellitus (T2DM) is a risk factor for deep neck infection (DNI) and leads to complications and poor outcomes. Our study aimed to investigate the risk, prognosis,...
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Time to Reach Target Glycosylated Hemoglobin Is Associated with Long-Term Durable Glycemic Control and Risk of Diabetic Complications in Patients with Newly Diagnosed Type 2 Diabetes Mellitus: A 6-Year Observational Study

Kim KJ, Choi J, Bae JH, Kim KJ, Yoo HJ, Seo JA, Kim NH, Choi KM, Baik SH, Kim SG, Kim NH

Background: To evaluate the association of time to reach the target glycosylated hemoglobin (HbA1c) level with long-term durable glycemic control and risk of diabetic complications in patients with newly diagnosed...
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Association between Sleep Quality and Painless Diabetic Peripheral Neuropathy Assessed by Current Perception Threshold in Type 2 Diabetes Mellitus

Choi D, Kim BY, Jung CH, Kim CH, Mok JO

Background It is known that the painful sensation of diabetic peripheral neuropathy (DPN) results in sleep problems in type 2 diabetes mellitus (T2DM). However, it is not known that the painless...
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Interaction Effects between Individual Socioeconomic Status and Regional Deprivation on Onset of Diabetes Complication and Diabetes-Related Hospitalization among Type 2 Diabetes Patients: National Health Insurance Cohort Sample Data from 2002 to 2013

Jang J, Ju YJ, Lee DW, Lee SA, Oh SS, Choi DW, Lee HJ, Shin J

Background: In this study, we aimed to investigate the interaction effects of individual socioeconomic status and regional deprivation on the onset of diabetes complications and diabetes-related hospitalization among type 2...
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Association of Vitamin D Deficiency with Diabetic Nephropathy

Hong Sh, Kim YB, Choi HS, Jeong TD, Kim JT, Sung YA

Background: Low 25-hydroxyvitamin D (25OHD) levels are associated with the incidence of type 2 diabetes mellitus (T2DM). However, the association between 25OHD and metabolic health status or diabetic complications is...
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Age at Diagnosis and the Risk of Diabetic Nephropathy in Young Patients with Type 1 Diabetes Mellitus

Baek JH, Lee WJ, Lee BW, Kim SK, Kim G, Jin SM, Kim JH

Background The aim of this study was to evaluate characteristics and risk of diabetic complications according to age at diagnosis among young adults with type 1 diabetes mellitus (T1DM). Methods A total of...
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Educational Needs Associated with the Level of Complication and Comparative Risk Perceptions in People with Type 2 Diabetes

Hwang Y, Lee D, Kim YS

Objectives This study aimed to identify the educational needs of people with type 2 diabetes according to risk perceptions and the level of severity of complications. Methods There were 177 study participants who...
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Impact of Diabetes Control on Subclinical Atherosclerosis: Analysis from Coronary Computed Tomographic Angiography Registry

Park GM, Lee CH, Lee SW, Yun SC, Kim YH, Kim YG, Won KB, Ann SH, Kim SJ, Yang DH, Kang JW, Lim TH, Koh EH, Lee WJ, Kim MS, Park JY, Kim HK, Choe J, Lee SG

BackgroundThere are limited data on the impact of diabetes control on the risk of subclinical coronary atherosclerosis.MethodsWe analyzed 6,434 consecutive asymptomatic individuals without previous history of coronary artery disease who...
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The Association between Serum Uric Acid and Peripheral Neuropathy in Patients with Type 2 Diabetes Mellitus: A Multicenter Nationwide CrossSectional Study

Kaewput W, Thongprayoon C, Rangsin R, Jindarat S, Narindrarangkura P, Bathini T, Mao MA, Cheungpasitporn W

Background: The role of uric acid in the development of diabetic peripheral neuropathy remains unclear. This study aimed to determine the association between uric acid and peripheral neuropathy among type...
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Acute Hyperglycemic Crises with Coronavirus Disease-19: Case Reports

Kim Ny, Ha E, Moon JS, Lee YH, Choi EY

Since the first case was contracted by coronavirus disease-19 (COVID-19) in Daegu, Korea in February 2020, about 6,800 cases and 130 deaths have been reported on April 9, 2020. Recent...
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Diabetic Muscle Infarction in a Young Patient with Prader-Willi Syndrome and Type 2 Diabetes Mellitus

Kwon EJ, Lee EJ, Jang HC, Kang EH, Lee YJ, Ha YJ

Diabetic muscle infarction (DMI), also known as diabetic myonecrosis, is a rare complication of diabetes mellitus (DM); hence, it is often underdiagnosed. Thus, timely diagnosis and treatment are essential for...
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Time in Range from Continuous Glucose Monitoring: A Novel Metric for Glycemic Control

Yoo JH, Kim JH

Glycosylated hemoglobin (HbA1c) has been the sole surrogate marker for assessing diabetic complications. However, consistently reported limitations of HbA1c are that it lacks detailed information on short-term glycemic control and...
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The Role of Anti-Obesity Medication in Prevention of Diabetes and Its Complications

Oh TJ

Diabetes is prevalent in obese population, and obesity management is the first step in preventing diabetes. Traditionally, lifestyle modification including reduced-calorie diet, physical activity, and behavior intervention is the core...
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Current Management of Type 2 Diabetes Mellitus in Primary Care Clinics in Korea

Seo DH, Kang S, Lee YH, Ha JY, Park JS, Lee BW, Kang ES, Ahn CW, Cha BS

BACKGROUND: This study investigated the overall status of diabetes control and screening for diabetic microvascular complications in patients with type 2 diabetes mellitus attending primary care clinics in Korea. METHODS: In...
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Diabetes-related Amylin Dyshomeostasis: a Contributing Factor to Cerebrovascular Pathology and Dementia

Ly H, Despa F

Type 2 diabetes (T2D) increases the risk for cerebrovascular disease (CVD) and dementia. The underlying molecular mechanisms remain elusive, which hampers the development of treatment or/and effective prevention strategies. Recent...
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Glycosylated Hemoglobin in Subjects Affected by Iron-Deficiency Anemia

Intra J, Limonta G, Cappellini F, Bertona M, Brambilla

Previous studies have suggested that iron-deficiency anemia affects glycosylated hemoglobin (HbA1c) measurements, but the results were contradictory. We conducted a retrospective case-control study to determine the effects of iron deficiency...
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Pharmacotherapy of Diabetes Focused on Stroke

Lyu YS, Kim JH, Kim SY

Cardiovascular disease, including stroke, is one of the major causes of death in diabetes. Numerous studies have long suggested reducing macrovascular complication such as ischemic vascular disease through intensive glycemic...
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Diabetes Mellitus and Cause-Specific Mortality: A Population-Based Study

Li S, Wang J, Zhang B, Li X, Liu Y

BACKGROUND: To investigate whether diabetes contributes to mortality for major types of diseases. METHODS: Six National Health and Nutrition Examination Survey data cycles (1999 to 2000, 2001 to 2002, 2003 to...
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Comparison of Improving Effects for Diabetic Erectile Dysfunction according to the Anti-Glycemic Agents: Phlorizin and Insulin

Park J, Kwon O, Cho SY, Cho MC, Paick JS, Kim SW

PURPOSE: To compare the improving effects of diabetic erectile dysfunction with two anti-glycemic agents; phlorizin and insulin. MATERIALS AND METHODS: Sixty Sprague-Dawley rats were divided into four groups (n=15 in each...
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