J Korean Neurosurg Soc.  2019 May;62(3):328-335. 10.3340/jkns.2019.0026.

Epilepsy Surgery in Children versus Adults

• Lee KH
• Lee YJ
• Seo JH
• Baumgartner JE
• Westerveld M

• KMID: 2453238
• DOI: http://doi.org/10.3340/jkns.2019.0026

Abstract

Epilepsy is one of the most common chronic neurological disorder affecting 6-7 per 1000 worldwide. Nearly one-third of patients with newly diagnosed epilepsy continue to have recurrent seizures despite adequate trial of more than two anti-seizure drugs : drug-resistant epilepsy (DRE). Children with DRE often experience cognitive and psychosocial co-morbidities requiring more urgent and aggressive treatment than adults. Epilepsy surgery can result in seizure-freedom in approximately two-third of children with improvement in cognitive development and quality of life. Understanding fundamental differences in etiology, co-morbidity, and neural plasticity between children and adults is critical for appropriate selection of surgical candidates, appropriate presurgical evaluation and surgical approach, and improved overall outcome.

Keyword

Epilepsy; Surgery; Drug resistant epilepsy; Child

MeSH Terms

Adult*
Child*
Drug Resistant Epilepsy
Epilepsy*
Humans
Nervous System Diseases
Plastics
Quality of Life
Seizures
Plastics

Reference

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