Neurospine.  2019 Jun;16(2):339-346. 10.14245/ns.1836154.077.

Neural Axis Abnormalities in Patients With Adolescent Idiopathic Scoliosis: Is Routine Magnetic Resonance Imaging Indicated Irrespective of Curve Severity?

• Fruergaard S
• Ohrt-Nissen S
• Dahl B
• Kaltoft N
• Gehrchen M

• KMID: 2452674
• DOI: http://doi.org/10.14245/ns.1836154.077

Abstract

OBJECTIVE
Magnetic resonance imaging (MRI)-verified neural axis abnormalities (NAAs) have been described in adolescent idiopathic scoliosis (AIS), and several risk factors have been associated with the presence of NAAs in AIS patients. However, the clinical significance of these findings is unclear. The purpose of the present study was to determine the prevalence of NAAs in a large consecutive cohort of AIS patients and to evaluate the clinical significance of previously proposed risk factors.
METHODS
We prospectively included AIS patients referred to a tertiary facility for evaluation. Full-spine MRI scans were performed on all included patients irrespective of curve magnitude or proposed treatment modality. MRI scans were prospectively analyzed by a neuroradiologist and the pathologic findings were confirmed by a second independent radiologist.
RESULTS
NAA was observed in 34 of the 381 patients (8.9%): 32 patients had a syrinx, 1 patient had an arachnoid cyst, and 1 patient had a Chiari malformation. Four patients were referred for a neurosurgical evaluation but none received any neurosurgical treatment. No statistically significant difference was observed between the NAA and non-NAA groups in terms of sex, major curve size, thoracic kyphosis, left thoracic curve, curve convexity, curve progression, or level of pain (p>0.05).
CONCLUSION
In this prospective study examining the risk factors for NAA in AIS patients, we found that previously proposed risk factors could not predict the MRI outcomes. The finding of an NAA had no clinical implications and we do not support MRI scans as a routine diagnostic modality in all AIS patients.

Keyword

Neural axis abnormality; Adolescent idiopathic scoliosis; Magnetic resonance imaging; Syrinx; Syringomyelia

MeSH Terms

Adolescent*
Arachnoid
Cohort Studies
Humans
Kyphosis
Magnetic Resonance Imaging*
Prevalence
Prospective Studies
Risk Factors
Scoliosis*
Syringomyelia