Korean J Pancreas Biliary Tract.  2016 Oct;21(4):209-215. 10.15279/kpba.2016.21.4.209.

Long Term Complete Response of Unresectable Locally Advanced Pancreatic Cancer after CCRT and Gemcitabine Chemotherapy

• Yang J
• Lim T
• Kim T
• Han S
• Lee S
• Kim H
• Lee J
• Ahn S

• KMID: 2448581
• DOI: http://doi.org/10.15279/kpba.2016.21.4.209

Abstract

Locally advanced or metastatic disease accounts for two thirds of total patients with pancreatic cancer. Patients with pancreatic cancer are assessed as resectable, potentially resectable (borderline) or unresectable according to pre-operative examinations. The chances of resectability may be enhanced by using neoadjuvant systemic chemotherapy, radiotherapy or both. This case report presents a locally advanced pancreatic adenocarcinoma that was identified to be unresectable during surgical exploration. After receiving concurrent chemoradiotherapy, the patient was re-evaluated, identified as unresectable and received gemcitabine maintenance chemotherapy. Herein, we report the case of a patient with unresectable locally advanced pancreatic adenocarcinoma who achieved a complete response lasting for more than 32 months after receiving concurrent chmoradiotherapy followed by gemcitabine maintenance chemotherapy.

Keyword

Pancreatic cancer; Chemoradiotherapy; Gemcitabine; Chemotherapy

MeSH Terms

Adenocarcinoma
Chemoradiotherapy
Drug Therapy*
Humans
Maintenance Chemotherapy
Pancreatic Neoplasms*
Radiotherapy