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Is cholecystectomy safe in extremely elderly patients?

Yang JD

Gallstone disease is the most common global indication for abdominal surgery. Especially acute cholecystitis in the elderly is frequently encountered due to an increasingly elderly population. Although cholecystectomy is the...
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Impairment of AMPK-α2 augments detrusor contractions in bladder ischemia

Yang JH, Niu W, Li Y, Azadzoi KM

Purpose: Ischemia disrupts cellular energy homeostasis. Adenosine monophosphate-activated protein kinase alpha-2 (AMPK-α2) is a subunit of AMPK that senses cellular energy deprivation and signals metabolic stress. Our goal was to...
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Injury Characteristics and Predisposing Effects of Various Outdoor Traumatic Situations in Children and Adolescents

Hwang IY, Park J, Park SS, Yang J, Kang MS

Background: Many studies have reported injury characteristics of individual traumatic situations. However, a comparative analysis of specific risks is meaningful to better understand injury characteristics and help establish injury-prevention measures....
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Effects of Iron Dietary Supplements to Prevent Iron Deficiency in Repeat Blood Donors

Lee JY, Lee JS, Ko DY, Seon JY, Yang JH, Kim JN, Youn MA

Background: The purpose of this study was to prepare data for the prevention and management of iron deficiency by analyzing the effects of taking iron supplements provided by blood centers...
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Immunohistochemical Analysis of Prurigo Nodularis in 209 Patients: Clinicopathological Analysis between Atopic and Non-Atopic Patients and between Treatment Response Groups

Byun HJ, Jang D, Lee DY, Yang JM

Background: Prurigo nodularis (PN) is a highly pruritic disease that significantly impairs patient quality of life. Although the mechanism that causes pruritus is not clear, one hypothesis argues that neural...
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Hypoxia Regulates the Extracellular Matrix via Mitogen-Activated Protein Kinases Pathway in Cells Retrieved from the Human Intervertebral Disc

Kang YM, Shin EJ, Lee BH, Yang JH, Lee HM, Moon SH

Purpose: The present study aimed to identify the physiological characteristics of cells by investigating the change in gene expression and protein levels during extracellular matrix (ECM) synthesis in the intervertebral...
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Association between Alcohol Consumption and Serum Cortisol Levels: a Mendelian Randomization Study

Yang JH, Kweon SS, Lee YH, Choi SW, Ryu SY, Nam HS, Park KS, Kim HY, Shin MH

Background: Several studies have reported conflicting results regarding the relationship between alcohol consumption and cortisol levels. However, the causality between alcohol consumption and cortisol levels has not been evaluated. Methods: This...
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Patterns of Locoregional Recurrence after Radical Cystectomy for Stage T3-4 Bladder Cancer: A Radiation Oncologist’s Point of View

Kim HJ, Chun J, Kim TH, Yang G, Shin SJ, Kim JS, Yang J, Ham WS, Koom WS

Purpose: Adjuvant radiotherapy (RT) has been performed to reduce locoregional failure (LRF) following radical cystectomy for locally advanced bladder cancer; however, its efficacy has not been well established. We analyzed...
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Development of predictive score for posttransplant survival based on pre-transplant recipient characteristics

Koo TY, Lee J, Yang J

Background: The new kidney allocation system in the United States has introduced longevity matching, which gives priority to allocating the best quality organs to wait-listed candidates with the longest predicted...
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Sequential treatment from mandibulectomy to reconstruction on mandibular oral cancer – Case review II: mandibular anterior and the floor of the mouth lesion of basaloid squamous cell carcinoma and clear cell odontogenic carcinoma

Yang JY, Hwang DS, Kim UK

Preoperative patient analysis for oral cancer involves multiple considerations that are based on multiple factors; these include TNM stages, histopathologic findings, and adjacent anatomical structures. Once the decision is made...
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A Pilot Project for Expansion of the External Quality Assessment Program in Transfusion Medicine: Extended Antigen Typing

Chung Y, Kim JS, Yang JJ, Kim H, Hwang SH, Oh HB, Ko DH

Background: As the need for expansion of the external quality assessment (EQA) scheme for transfusion medicine in Korea has increased, we performed a pilot project of extended antigen typing for...
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Identification of 8-Digit HLA-A, -B, -C, and -DRB1 Allele and Haplotype Frequencies in Koreans Using the One Lambda AllType Next-Generation Sequencing Kit

Choe W, Chae JD, Yang JJ, Hwang SH, Choi SE, Oh HB

Background: Recent studies have successfully implemented next-generation sequencing (NGS) in HLA typing. We performed HLA NGS in a Korean population to estimate HLA-A, -B, -C, and -DRB1 allele and haplotype...
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Ethnography on the Health Life of Hemodialysis Patients with Chronic Kidney Failure

Yang J, Cho MO

Purpose: This study was performed to explore the contexts and meanings of health life among patients with chronic kidney failure undergoing hemodialysis. Methods: The ethnography steps presented by Spradley were utilized....
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Long-term Outcomes of Clopidogrel Monotherapy versus Prolonged Dual Antiplatelet Therapy beyond 12 Months after Percutaneous Coronary Intervention in High-risk Patients

Kim DY, Cho SW, Park KT, Ahn JH, Park TK, Jang YH, Choi KH, Lee JM, Yang JH, Song YB, Choi JH, Choi SH, Gwon HC, Lee SH, Hahn JY

Background: There are no data on comparison between clopidogrel monotherapy and prolonged dual antiplatelet therapy (DAPT) in patients at high-risk undergoing percutaneous coronary intervention (PCI). Methods: Of 2,082 consecutive patients undergoing...
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Impact of a Multidisciplinary Team Approach on Extracorporeal Circulatory Life Support-Bridged Heart Transplantation

Lee JJ, Kim YS, Chung S, Jeong DS, Yang JH, Sung K, Kim WS, Jun TG, Cho YH

Background: The number of heart transplantations (HTx) is increasing annually. Due to advances in medical and surgical support, the outcomes of HTx are also improving. Extracorporeal circulatory life support (ECLS)...
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2021 Korean Society of Myocardial Infarction Expert Consensus Document on Revascularization for Acute Myocardial Infarction

Chang K, Ahn Y, Lim S, Yang JH, Lee KY, Choo EH, Kim HK, Nam CW, Kim W, Hwang JY, Rha SW, Kim HS, Cho MC, Jang Y, Jeong MH, tTFoECDotKSoMI(

Acute myocardial infarction (AMI) is a fatal manifestation of ischemic heart disease and remains a major public health concern worldwide despite advances in its diagnosis and management. The characteristics of...
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Exploratory Investigation for Improvement of the External Quality Assessment Scheme for Transfusion Medicine

Yang JJ, Kim JS, Chung Y, Kim H, Ko DH, Hwang SH, Oh HB

Background: This study summarizes a survey conducted to improve and expand the external quality assessment (EQA) scheme for transfusion in Korea. Methods: The EQA items provided by the College of American...
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Factors associated with long-term graft patency after lower extremity arterial bypasses

Jung KS, Heo SH, Woo SY, Park YJ, Kim DI, Kim YW

Purpose: This study was conducted to determine factors associated with long-term graft patency after lower extremity arterial bypass (LEAB). Methods: Database of LEABs for patients with chronic arterial occlusive disease (CAOD)...
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Selective inhibition of V600E-mutant BRAF gene induces apoptosis in thyroid carcinoma cell lines

Park KS, Saindane M, Yang EY, Jin T, Rallabandi HR, Heil A, Nam SE, Yoo YB, Yang JH, Kim JB, Park SY, Park WS, Youn YK

Purpose: Papillary thyroid cancer (PTC) has a high incidence of BRAF V600E mutation. The purpose of this study was to evaluate the potential relationship between thyroiditis and BRAF ...
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Prediction of HLA-DQ in Deceased Donors and its Clinical Significance in Kidney Transplantation

Kim SK, Yang JJ, Hwang SH, Sung H, Shin S, Ko SY, Oh HB

Background: HLA-DQ typing in deceased donors is not mandatory in Korea. Therefore, when patients develop DQ antibodies after kidney transplantation (KT) from deceased donor, it is impossible to determine whether...
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