Arch Craniofac Surg.  2019 Apr;20(2):130-133. 10.7181/acfs.2018.02334.

Treatment of the wide open wound in the Ehlers-Danlos syndrome

• Baik BS
• Lee WS
• Park KS
• Yang WS
• Ji SY

• KMID: 2447638
• DOI: http://doi.org/10.7181/acfs.2018.02334

Abstract

Ehlers-Danlos syndrome (EDS) is an inherited disorder of collagen biosynthesis and structure, characterized by skin hyperextensibility, joint hypermobility, aberrant scars, and tissue friability. Besides the skin, skeleton (joint) and vessels, other organs such as the eyes and the intestine can be affected in this syndrome. Accordingly, interdisciplinary cooperation is necessary for a successful treatment. Three basic surgical problems are arising due to an EDS: decreased the strength of the tissue causes making the wound dehiscence, increased bleeding tendency due to the blood vessel fragility, and delayed wound healing period. Surgery patients with an EDS require an experienced surgeon in treating EDS patients; the treatment process requires careful tissue handling and a long postoperative care. A surgeon should also recognize whether the patient shows a resistance to local anesthetics and a high risk of hematoma formation. This report describes a patient with a wide open wound on the foot dorsum and delayed wound healing after the primary approximation of the wound margins.

Keyword

Connective tissue diseases; Ehlers-Danlos syndrome; Joint instability

MeSH Terms

Anesthetics, Local
Blood Vessels
Cicatrix
Collagen
Connective Tissue Diseases
Ehlers-Danlos Syndrome*
Foot
Hematoma
Hemorrhage
Humans
Intestines
Joint Instability
Postoperative Care
Skeleton
Skin
Wound Healing
Wounds and Injuries*
Anesthetics, Local
Collagen