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Current Understanding of Mineral and Bone Disorders of Chronic Kidney Disease and the Scientific Grounds on the Use of Exogenous Parathyroid Hormone in Its Management

Pazianas M, Miller PD

Chronic Kidney disease (CKD) disturbs mineral homeostasis leading to mineral and bone disorders (MBD). Serum calcium and phosphate (Pi) remain normal until the late stages of CKD at the expense...
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Hypertrophic osteopathy in a cat with cardiac interventricular septal defect

de Sousa F, Bianchi MV, Taunde PA, Bandinelli MB, Fett RR, Driemeier , Pavarini S

A 3-year-old mixed-breed female cat was diagnosed with a ventricular septal defect of the heart through an echocardiogram. After a 9-month treatment, progressive and diffuse hard thickening of all limbs...
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Bacillus Calmette-Guérin (BCG)-Cell Wall Skeleton as Immunotherapeutic Option for BCG-Refractory Superficial Bladder Cancer

Whang YM, Yoon DH, Hwang GY, Choi YW, Chang IH

Although intravesical instillation of Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the most successful cancer immunotherapy for superficial bladder cancer, the serious side effects are frequently arisen by using live mycobacteria....
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Myxoma arising from the parotid gland

Kim SM, Kim CK, Kim SH, Lee MC, Kim JN, Choi HG, Shin DH, Jo DI

Myxomas can be divided into two groups: those derived from the facial skeleton, and those derived from external skeletal soft tissue. Soft tissue myxomas of the head and neck are...
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How to Return Mummified or Skeletal Human Remains to their Descendants after Anthropological Investigation

Oh CS, Shin DH, Kim YG, Park JB

The mummies and skeletons excavated at the archaeological excavation site are an anthropologically important research subject. However, after the scientific analysis on them, it is sometimes necessary return them to...
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A Case Study of the Fetal Skeleton from a Joseon Period Cemetery

Woo EJ, Jeon CL

In this study, the case of the burial of a couple with their perinatal child in a cemetery from the Joseon period (Eunpyeong site) of South Korea was examined. In...
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Mitochondrial DNA Analysis of the Human Skeletons from Goryeo Dynasty Graves Discovered at Youngwol, Gangwon-do

Oh CS, Hong JH, Shin DH

In archaeological excavation sites in Korea, human skeletal remains of various periods were discovered. However, there have been very few studies on skeletal cases of Goryeo period so far. Therefore,...
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A Life and Death of the Leprosy Patients in Joseon Society Considered from the Anthropological Perspective

Shin DH, Shin EK

Leprosy is an important topic in the research field of bioanthropology and paleopathology. In this study, by reviewing historical documents, we are to investigate the life and death of leprosy...
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Tales from Fragments: A Review of Indian Human Skeletal Studies

Mushrif-Tripathy V

India provides large number of skeletal data from the pre- and protohistoric levels covering a time span of almost 10,000 years. Major skeletal collection comes from the cultural phases ranging...
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Incidentally-Discovered Extraosseous Cystic Nasopharyngeal Chordoma in a Papillary Thyroid Cancer Patient

Kim H, Kim JH, Lee K, Kim TH

Skull base chordomas are rare, malignant tumors arising from primitive notochord remnants of the axial skeleton and comprise approximately 25–35% of all chordoma cases. Nasal endoscopy in previous case reports...
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Treatment of the wide open wound in the Ehlers-Danlos syndrome

Baik BS, Lee WS, Park KS, Yang WS, Ji SY

Ehlers-Danlos syndrome (EDS) is an inherited disorder of collagen biosynthesis and structure, characterized by skin hyperextensibility, joint hypermobility, aberrant scars, and tissue friability. Besides the skin, skeleton (joint) and vessels,...
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Chordomas: Histopathological Study in View of Anatomical Location

Cha YJ, Suh YL

BACKGROUND: Chordomas are aggressive bone tumors that have a predilection for the axial skeleton including the skull base and spinal/sacral bones. However, the histopathological and clinical differences between skull base...
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A Report of Bone Marrow Metastasis of Colon Cancer as a Primary Diagnosis, Supported by Cytokeratin Immunohistochemical Staining

Kim B, Lee KT

Bone marrow metastasis of colon cancer is rare. Here, we report a 56-year-old female patient who presented with pancytopenia. She was diagnosed with colon cancer accompanied by lung and axial...
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The Impact of Childhood Obesity on Skeletal Health and Development

Dimitri P

Increased risk of fracture identified in obese children has led to a focus on the relationship between fat, bone, and the impact of obesity during skeletal development. Early studies have...
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Anti-inflammatory activities of sinensetin on LPS-stimulated L6 skeletal muscle cells

Kim JA, Ha SE, Kim SM, Vetrivel P, Kim GS, Kim EH

Inflammation is an important protective response mechanism that occurs against microbial invasion or injury. However, excessive inflammation may lead to cause of morbidity and mortality in diseases. The activated macrophages...
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Aluminum toxicity to bone: A multisystem effect?

Klein GL

Aluminum (Al) is the third most abundant element in the earth's crust and is omnipresent in our environment, including our food. However, with normal renal function, oral and enteral ingestion...
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The Relationship between the Occipitocervical Junction and Thoracic Kyphosis in Ankylosing Spondylitis: A Retrospective Cohort Study of 86 Cervical Fractures in Surgically Treated Patients

Manabe N, Covaro A, Bobinski L, Shimizu T, Olerud C, Robinson Y

STUDY DESIGN: Retrospective analysis of prospectively collected data. PURPOSE: To describe the radiological characteristics of the occipitocervical area in patients with ankylosing spondylitis (AS) using the novel measure X-angle and to...
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Hybrid Additive Microfabrication Scaffold Incorporated with Highly Aligned Nanofibers for Musculoskeletal Tissues

Sooriyaarachchi D, Minière H, Maharubin , Tan GZ

BACKGROUND: Latest tissue engineering strategies for musculoskeletal tissues regeneration focus on creating a biomimetic microenvironment closely resembling the natural topology of extracellular matrix. This paper presents a novel musculoskeletal tissue...
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Paleoparasitology of Merovingian Corpses Buried in Stone Sarcophagi in the Saint-Martin-au-Val Church (Chartres, France)

Dufour B, Portat E, Bazin B, Le Bailly

Paleoparasitological analysis was carried on 4 Merovingian skeletons, dated from the late-5th to the late-9th centuries, and recovered in the church of Saint-Martin-au-Val in Chartres (Center region, France). The corpses...
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Genetic Analysis of CLCN7 in an Old Female Patient with Type II Autosomal Dominant Osteopetrosis

Kim SY, Lee Y, Kang YE, Kim JM, Joung KH, Lee JH, Kim KS, Kim HJ, Ku BJ, Shong M, Yi HS

BACKGROUND: Type II autosomal dominant osteopetrosis (ADO II) is a rare genetically heterogeneous disorder characterized by osteosclerosis and increased bone mass, predominantly involving spine, pelvis, and skull. It is closely...
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