Nutr Res Pract.  2018 Oct;12(5):436-442. 10.4162/nrp.2018.12.5.436.

High dairy products intake reduces osteoporosis risk in Korean postmenopausal women: A 4 year follow-up study

Affiliations
  • 1Department of Food and Nutrition, College of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi 13120, Korea. skysea@gachon.ac.kr
  • 2Institute for Clinical Nutrition, Inje University, Seoul 04551, Korea.
  • 3Research Division of Food Functionality, Korea Food Research Institute, Wanju 55365, Korea.

Abstract

BACKGROUND/OBJECTIVES
The aim of this study was to identify the effect of dairy products, milk and yogurt on osteoporosis incidence among Korean postmenopausal women using prospective cohort data.
MATERIALS/METHODS
Between 2001 and 2003, 10,038 participants were recruited in rural and urban areas for a baseline examination of a community-based cohort study. Of those, 1,573 postmenopausal women (aged 40-69 years at baseline) were eligible for the present study. Intakes of dairy products, milk, and yogurt were assessed using a validated semi-quantitative food frequency questionnaire. The speed of sound at the radius and tibia were measured using a quantitative ultrasound device and osteoporosis was defined based on the WHO criteria (T-score ≤−2.5).
RESULTS
During the 4-years follow-up study, the cumulative incidence of osteoporosis was 18.4% (273 cases) in the radius and 33.6% (407 cases) in the tibia. The subjects with higher frequency of dairy product consumption showed a decreased risk of radius osteoporosis after adjusting for potential confounders [hazard ratio (HR) = 0.51, 95% confidence interval (CI): 0.33-0.80 for >1 time/day vs. non consumer; P for trend = 0.0027]. Similarly, high frequency of milk and yogurt consumption had a protective effect on radius osteoporosis risk [milk: HR = 0.60, 95% CI: 0.42-0.87 for >5-6 times/week vs. non consumer (P for trend = 0.0130), yogurt: HR = 0.51, 95% CI: 0.30-0.85 for > 5-6 times/week vs. non consumer (P for trend = 0.0167)]. However, high dairy products consumption was not related with tibia osteoporosis.
CONCLUSIONS
This study suggests that daily intake of dairy products could potentially reduce radius osteoporosis incidence among Korean postmenopausal women.

Keyword

Dairy products; milk; osteoporosis; postmenopause; Korea

MeSH Terms

Cohort Studies
Dairy Products*
Female
Follow-Up Studies*
Humans
Incidence
Korea
Milk
Osteoporosis*
Postmenopause
Prospective Studies
Radius
Tibia
Ultrasonography
Yogurt

Reference

1. Cummings SR, Melton LJ. Epidemiology and outcomes of osteoporotic fractures. Lancet. 2002; 359:1761–1767. PMID: 12049882.
Article
2. Coughlan T, Dockery F. Osteoporosis and fracture risk in older people. Clin Med (Lond). 2014; 14:187–191. PMID: 24715132.
Article
3. Rizzoli R. Dairy products, yogurts, and bone health. Am J Clin Nutr. 2014; 99:1256S–1262S. PMID: 24695889.
Article
4. Cumming RG, Nevitt MC. Calcium for prevention of osteoporotic fractures in postmenopausal women. J Bone Miner Res. 1997; 12:1321–1329. PMID: 9286747.
Article
5. Kanis JA, Johansson H, Oden A, De Laet C, Johnell O, Eisman JA, Mc Closkey E, Mellstrom D, Pols H, Reeve J, Silman A, Tenenhouse A. A meta-analysis of milk intake and fracture risk: low utility for case finding. Osteoporos Int. 2005; 16:799–804. PMID: 15502959.
Article
6. Michaëlsson K, Wolk A, Langenskiöld S, Basu S, Warensjö Lemming E, Melhus H, Byberg L. Milk intake and risk of mortality and fractures in women and men: cohort studies. BMJ. 2014; 349:g6015. PMID: 25352269.
Article
7. Włodarek D, Głąbska D, Kołota A, Adamczyk P, Czekajło A, Grzeszczak W, Drozdzowska B, Pluskiewicz W. Calcium intake and osteoporosis: the influence of calcium intake from dairy products on hip bone mineral density and fracture incidence - a populationbased study in women over 55 years of age. Public Health Nutr. 2014; 17:383–389. PMID: 23217270.
Article
8. Durosier-Izart C, Biver E, Merminod F, van Rietbergen B, Chevalley T, Herrmann FR, Ferrari SL, Rizzoli R. Peripheral skeleton bone strength is positively correlated with total and dairy protein intakes in healthy postmenopausal women. Am J Clin Nutr. 2017; 105:513–525. PMID: 28077378.
Article
9. Korea Health Industry Development Institute (KHIDI). National Food & Nutrition Statistics 2013: based on 2013 Korea National Health and Nutrition Examination Survey [Internet]. Cheongju: Korea Health Industry Development Institute;2015. cited 2018 January 10. Available from: https://www.khidi.or.kr/.
10. Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Health Statistics 2010: Korean National Health & Nutrition Examination Survey. Seoul: Korea Centers for Disease Control and Prevention;2010.
11. Wright NC, Looker AC, Saag KG, Curtis JR, Delzell ES, Randall S, Dawson-Hughes B. The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine. J Bone Miner Res. 2014; 29:2520–2526. PMID: 24771492.
Article
12. Lim YS, Lee SW, Tserendejid Z, Jeong SY, Go G, Park HR. Prevalence of osteoporosis according to nutrient and food group intake levels in Korean postmenopausal women: using the 2010 Korea National Health and Nutrition Examination Survey Data. Nutr Res Pract. 2015; 9:539–546. PMID: 26425285.
Article
13. Shin A, Lim S, Sung J, Myung S, Kim J. Dietary habit and bone mineral density in Korean postmenopausal women. Osteoporos Int. 2010; 21:947–955. PMID: 19727908.
Article
14. Hong H, Kim EK, Lee JS. Effects of calcium intake, milk and dairy product intake, and blood vitamin D level on osteoporosis risk in Korean adults: analysis of the 2008 and 2009 Korea National Health and Nutrition Examination Survey. Nutr Res Pract. 2013; 7:409–417. PMID: 24133621.
Article
15. Baek SW, Lee HO, Kim HJ, Won ES, Ha YS, Shin YK, Om AS. Relationship between intake of milk and milk products and bone health by sex and age-group in Koreans using data from the Korea National Health and Nutrition Examination Survey 2008~2011. J Korean Soc Food Sci Nutr. 2017; 46:513–522.
16. Seo HB, Choi YS. Sex- and age group-specific associations between intakes of dairy foods and pulses and bone health in Koreans aged 50 years and older: based on 2008~2011 Korea National Health and Nutrition Examination Survey. J Nutr Health. 2016; 49:165–178.
Article
17. Kim Y, Han BG. KoGES group. Cohort profile: The Korean Genome and Epidemiology Study (KoGES) consortium. Int J Epidemiol. 2017; 46:e20. PMID: 27085081.
Article
18. McCrory MA, McCrory MA, Hajduk CL, Roberts SB. Procedures for screening out inaccurate reports of dietary energy intake. Public Health Nutr. 2002; 5:873–882. PMID: 12633510.
Article
19. Ahn Y, Lee JE, Cho NH, Shin C, Park C, Oh BS, Kimm K. Validation and calibration of semi-quantitative food frequency questionnaire: with participants of the Korean Health and Genome Study. Korean J Community Nutr. 2004; 9:173–182.
20. Ahn Y, Kwon E, Shim JE, Park MK, Joo Y, Kimm K, Park C, Kim DH. Validation and reproducibility of food frequency questionnaire for Korean genome epidemiologic study. Eur J Clin Nutr. 2007; 61:1435–1441. PMID: 17299477.
Article
21. The Korean Nutrition Society. Recommended Dietary Allowances for Koreans. 7th revision. Seoul: The Korean Nutrition Society;2000.
22. Damilakis J, Papadokostakis G, Vrahoriti H, Tsagaraki I, Perisinakis K, Hadjipavlou A, Gourtsoyiannis N. Ultrasound velocity through the cortex of phalanges, radius, and tibia in normal and osteoporotic postmenopausal women using a new multisite quantitative ultrasound device. Invest Radiol. 2003; 38:207–211. PMID: 12649644.
Article
23. Chong KH, Poh BK, Jamil NA, Kamaruddin NA, Deurenberg P. Radial quantitative ultrasound and dual energy x-ray absorptiometry: intermethod agreement for bone status assessment in children. Biomed Res Int. 2015; 2015:232876. PMID: 25922831.
Article
24. Pisani P, Renna MD, Conversano F, Casciaro E, Muratore M, Quarta E, Paola MD, Casciaro S. Screening and early diagnosis of osteoporosis through x-ray and ultrasound based techniques. World J Radiol. 2013; 5:398–410. PMID: 24349644.
25. Hans D, Genton L, Allaoua S, Pichard C, Slosman DO. Hip fracture discrimination study: QUS of the radius and the calcaneum. J Clin Densitom. 2003; 6:163–172. PMID: 12794239.
26. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Ser. 1994; 843:1–129. PMID: 7941614.
27. Cashman KD. Diet, nutrition, and bone health. J Nutr. 2007; 137:2507S–2512S. PMID: 17951494.
Article
28. Weaver CM. The role of nutrition on optimizing peak bone mass. Asia Pac J Clin Nutr. 2008; 17(Suppl 1):135–137. PMID: 18296321.
29. Renner E. Dairy calcium, bone metabolism, and prevention of osteoporosis. J Dairy Sci. 1994; 77:3498–3505. PMID: 7699131.
Article
30. Caroli A, Poli A, Ricotta D, Banfi G, Cocchi D. Invited review: dairy intake and bone health: a viewpoint from the state of the art. J Dairy Sci. 2011; 94:5249–5262. PMID: 22032348.
Article
31. Uusi-Rasi K, Sievänen H, Pasanen M, Oja P, Vuori I. Associations of calcium intake and physical activity with bone density and size in premenopausal and postmenopausal women: a peripheral quantitative computed tomography study. J Bone Miner Res. 2002; 17:544–552. PMID: 11874246.
Article
32. Uusi-Rasi K, Sievänen H, Vuori I, Pasanen M, Heinonen A, Oja P. Associations of physical activity and calcium intake with bone mass and size in healthy women at different ages. J Bone Miner Res. 1998; 13:133–142. PMID: 9443799.
Article
33. Sahni S, Mangano KM, Tucker KL, Kiel DP, Casey VA, Hannan MT. Protective association of milk intake on the risk of hip fracture: results from the Framingham Original Cohort. J Bone Miner Res. 2014; 29:1756–1762. PMID: 24760749.
Article
34. Kung AW, Lee KK, Ho AY, Tang G, Luk KD. Ten-year risk of osteoporotic fractures in postmenopausal Chinese women according to clinical risk factors and BMD T-scores: a prospective study. J Bone Miner Res. 2007; 22:1080–1087. PMID: 17371165.
Article
35. Chen T, Chen PJ, Fung CS, Lin CJ, Yao WJ. Quantitative assessment of osteoporosis from the tibia shaft by ultrasound techniques. Med Eng Phys. 2004; 26:141–145. PMID: 15036181.
Article
36. Hung VW, Qin L, Au SK, Choy WY, Leung KS, Leung PC, Cheng JC. Correlations of calcaneal QUS with pQCT measurements at distal tibia and non-weight-bearing distal radius. J Bone Miner Metab. 2004; 22:486–490. PMID: 15316870.
Article
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