Urogenit Tract Infect.  2019 Apr;14(1):20-25. 10.14777/uti.2019.14.1.20.

Comparison of Monomicrobial versus Polymicrobial Candiduria: Time to Awareness of Candiduria

• Kim H
• Lee MK
• Kim TH

• KMID: 2445084
• DOI: http://doi.org/10.14777/uti.2019.14.1.20

Abstract

PURPOSE
Candiduria, which is the presence of Candida species in urine, is becoming increasingly common in hospital settings. These normal commensals in humans are often associated with the presence of other microorganisms. In this study, patients presenting with monomicrobial and polymicrobial candiduria were compared.
MATERIALS AND METHODS
A retrospective study was performed on the demographic, clinical, and laboratory data of 185 patients presenting with candiduria between July 2014 and June 2015 at Chung-Ang University Hospital. The threshold for a positive Candida species urine culture was set to 103 CFU/ml. Data on the following were evaluated: distribution of Candida species; patient age and sex; length of hospital stay; presence of diabetes mellitus (DM), chronic kidney disease (CKD), a urinary catheter, and fever; antibiotic administration; urinalysis; complete blood cells; and C-reactive protein.
RESULTS
Monomicrobial candiduria was more common (128/185, 69.2%) than polymicrobial candiduria (57/185, 30.8%). The most prevalent species was Candida albicans (monomicrobial vs. polymicrobial candiduria, 61.7% vs. 54.4%), followed in order by Candida tropicalis (18.8% vs. 24.6%), and Candida glabrata (14.8% vs. 12.3%), with no significant difference between the two groups. Significant differences in the length of stay, underlying DM or CKD, accompanying symptoms, and urine white blood cells (WBC) and bacterial counts were observed between the two groups (p<0.05).
CONCLUSIONS
The length of stay, underlying DM or CKD, accompanying symptoms, and urine WBC and bacterial counts were more associated with polymicrobial candiduria. The early detection and treatment of candiduria will become increasingly important as the Korean population ages.

Keyword

Candida; Urinary tract infections; Candidiasis; Polymicrobial infection

MeSH Terms

Bacterial Load
Blood Cells
C-Reactive Protein
Candida
Candida albicans
Candida glabrata
Candida tropicalis
Candidiasis
Coinfection
Diabetes Mellitus
Fever
Humans
Length of Stay
Leukocytes
Renal Insufficiency, Chronic
Retrospective Studies
Urinalysis
Urinary Catheters
Urinary Tract Infections
C-Reactive Protein

Reference

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