Korean J Intern Med.  2019 Mar;34(2):305-314. 10.3904/kjim.2017.110.

Clinical features of snoring patients during sedative endoscopy

Affiliations
  • 1Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. nakim@snubh.org kimjw@snubh.org
  • 2Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • 3Department of Otorhinolaryngology, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 4Medical Research Collaborating Center, Seoul National University Bundang Hospital, Seongnam, Korea.

Abstract

BACKGROUND/AIMS
Snoring is the sound of turbulence and vibration of the upper respiratory tissues and has been identified as a risk factor of obstructive sleep apnea (OSA) and cardiovascular disease. The aim of this study was to identify associated clinical factors in snoring patients undergoing sedative endoscopy.
METHODS
A total of 49 patients who snored during standard sedative endoscopy and 127 controls were prospectively enrolled from June 2015 to June 2016. The Korean version of the Berlin Questionnaire was used to identify risk factors of OSA. Clinical information, including comorbidities, was collected from electronic medical records.
RESULTS
The snoring group showed a higher risk of OSA (42.9% vs. 26.8%, p = 0.039), and a higher prevalence of coronary artery disease (10.2% vs. 0.8%, p = 0.007) and advanced gastric cancer (12.2% vs. 2.4%, p = 0.015) compared with the control group. Multivariate analysis showed that coronary artery disease (odds ratio [OR], 13.93; 95% confidence interval [CI], 1.24 to 155.90; p = 0.033) and advanced gastric cancer (OR, 5.21; 95% CI, 1.01 to 26.98; p = 0.049) were significantly associated with snoring. However, a history of gastrectomy showed only a marginally significant association with snoring (OR, 2.16; 95% CI, 0.91 to 5.11; p = 0.079).
CONCLUSIONS
Patients who snore during sedative endoscopy may need to be evaluated for possible coronary artery disease.

Keyword

Snoring; Stomach neoplasms; Coronary artery disease; Sleep apnea, obstructive; Surveys and questionnaires

MeSH Terms

Berlin
Cardiovascular Diseases
Comorbidity
Coronary Artery Disease
Electronic Health Records
Endoscopy*
Gastrectomy
Humans
Multivariate Analysis
Prevalence
Prospective Studies
Risk Factors
Sleep Apnea, Obstructive
Snoring*
Stomach Neoplasms
Surveys and Questionnaires
Vibration
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