Genomics Inform.  2018 Dec;16(4):e30. 10.5808/GI.2018.16.4.e30.

Storing Digital Information in Long-Read DNA

• Ahn T
• Ban H
• Park H

• KMID: 2439220
• DOI: http://doi.org/10.5808/GI.2018.16.4.e30

Abstract

There is urgent need for effective and cost-efficient data storage, as the worldwide requirement for data storage is rapidly growing. DNA has introduced a new tool for storing digital information. Recent studies have successfully stored digital information, such as text and gif animation. Previous studies tackled technical hurdles due to errors from DNA synthesis and sequencing. Studies also have focused on a strategy that makes use of 100-150-bp read sizes in both synthesis and sequencing. In this paper, we a suggest novel data encoding/decoding scheme that makes use of long-read DNA (~1,000 bp). This enables accurate recovery of stored digital information with a smaller number of reads than the previous approach. Also, this approach reduces sequencing time.

Keyword

DNA; information; information storage and retrieval; nanopore sequencing

MeSH Terms

DNA*
Information Storage and Retrieval
DNA