- Human papillomavirus (HPV) DNA detection in uterine cervix cancer after radiation indicating recurrence: a systematic review and meta-analysis
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Sabeena S, Kuriakose , Damodaran , Ravishankar N, Arunkumar
- KMID: 2470871
- J Gynecol Oncol.
- 2020 Mar;31(2):e20.
- doi: 10.3802/jgo.2020.31.e20
OBJECTIVE: The causal association of human papillomavirus (HPV) in uterine cervical cancer was well established and this oncogenic virus was reported to be a biomarker for overall recurrence and central... -
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- Epigenetic Changes in Asthma: Role of DNA CpG Methylation
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Bae DJ, Jun JA, Chang HS, Park JS, Park CS
- KMID: 2466615
- Tuberc Respir Dis.
- 2020 Jan;83(1):1-13.
- doi: 10.4046/trd.2018.0088
For the past three decades, more than a thousand of genetic studies have been performed to find out the genetic variants responsible for the risk of asthma. Until now, all... -
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- Quantification of Cell-Free DNA: A Comparative Study of Three Different Methods
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Jeon K, Lee J, Lee JS, Kim M, Kim HS, Kang HJ, Lee YK
- KMID: 2470322
- Lab Med Qual Assur.
- 2019 Dec;41(4):214-219.
- doi: 10.15263/jlmqa.2019.41.4.214
BACKGROUND: Cell-free DNA (cfDNA) provides unique potential as a biomarker for cancer patients or in the field of prenatal care. Following extraction from plasma, cfDNA should be quantified before downstream... -
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- Specific tail swelling pattern in hypo-osmotic solution as a predictor of DNA fragmentation status in human spermatozoa
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Kim SW, Nho EJ, Lee JY, Jee BC
- KMID: 2469590
- Clin Exp Reprod Med.
- 2019 Dec;46(4):147-151.
- doi: 10.5653/cerm.2019.00458
OBJECTIVE: The aim of this study was to investigate DNA fragmentation status in human spermatozoa according to specific tail swelling patterns determined via hypo-osmotic swelling test (HOST). METHODS: Frozen semen samples... -
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- Detection of KRAS mutations in plasma cell-free DNA of colorectal cancer patients and comparison with cancer panel data for tissue samples of the same cancers
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Min S, Shin S, Chung YJ
- KMID: 2468868
- Genomics Inform.
- 2019 Dec;17(4):e42.
- doi: 10.5808/GI.2019.17.4.e42
Robust identification of genetic alterations is important for the diagnosis and subsequent treatment of tumors. Screening for genetic alterations using tumor tissue samples may lead to biased interpretations because of... -
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- DNA methylation: a cause and consequence of type 2 diabetes
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Kim M
- KMID: 2468864
- Genomics Inform.
- 2019 Dec;17(4):e38.
- doi: 10.5808/GI.2019.17.4.e38
DNA methylation is a relatively stable epigenetic modification that can regulate and stabilize gene expression patterns and hence establish cell identity. Because metabolic intermediates are key factors of DNA methylation... -
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- Effects of β-carotene on Expression of Selected MicroRNAs, Histone Acetylation, and DNA Methylation in Colon Cancer Stem Cells
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Kim D, Kim Y, Kim Y
- KMID: 2468812
- J Cancer Prev.
- 2019 Dec;24(4):224-232.
- doi: 10.15430/JCP.2019.24.4.224
BACKGROUND: Beta-carotene (BC) is a carotenoid which exerts anti-cancer effects in several types of cancer, including colorectal cancer. Epigenetic modifications of genes, such as histone deacetylation and DNA hypermethylation, have... -
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- Comparison of Effective DNA Extraction method for Molecular biological study of Mycobacterium leprae
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Kim YJ, Park JH, Kim JP
- KMID: 2466490
- Korean Lepr Bull.
- 2019 Dec;52(1):29-40.
- doi: 10.33161/klb.2019.52.1.29
BACKGROUND: Leprosy is an important health problem in many geographical areas yet. It is caused through a cough or contact with fluid from the nose of a person infected by... -
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- Improvement of Human Sperm Vacuolization and DNA Fragmentation Co-Cultured with Adipose-Derived Mesenchymal Stem Cell Secretome: In Vitro Effect
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Bader R, Ibrahim JN, Mourad A, Moussa M, Azoury J, Azoury J, Alaaeddine N
- KMID: 2465879
- Int J Stem Cells.
- 2019 Nov;12(3):388-399.
- doi: 10.15283/ijsc19047
BACKGROUND AND OBJECTIVES: Oxidative stress (OS) is known to be an important factor of male infertility. Adipose-derived mesenchymal stem cells (AD-MSCs) are known to have immune-modulatory and anti-oxidant effects through... -
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- Result Patterns and Characteristics of HBeAg and HBV DNA in Patients with Chronic Hepatitis B
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Choi EJ, Kim JH, Han MS
- KMID: 2458680
- Lab Med Online.
- 2019 Oct;9(4):210-217.
- doi: 10.3343/lmo.2019.9.4.210
BACKGROUND: Discrepancies in the results between hepatitis B e-antigen (HBeAg) and hepatitis B virus (HBV) DNA levels pose difficulties in the management of chronic hepatitis B (CHB). This study aims... -
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- Effect of the Interaction Between Selenium and Zinc on DNA Repair in Association With Cancer Prevention
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Yildiz A, Kaya Y, Tanriverdi O
- KMID: 2468796
- J Cancer Prev.
- 2019 Sep;24(3):146-154.
- doi: 10.15430/JCP.2019.24.3.146
Cancer is the most common cause of death worldwide. Annually, more than ten million new cancer cases are diagnosed, and more than six million deaths occur due to cancer. Nonetheless,... -
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- Role of DNA Methylation in the Development and Differentiation of Intestinal Epithelial Cells and Smooth Muscle Cells
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Jorgensen , Ro S
- KMID: 2454636
- J Neurogastroenterol Motil.
- 2019 Jul;25(3):377-386.
- doi: 10.5056/jnm19077
The mammalian intestine contains many different cell types but is comprised of 2 main cell types: epithelial cells and smooth muscle cells. Recent in vivo and in vitro evidence has... -
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- Therapeutic Targeting of the DNA Damage Response Using an ATR Inhibitor in Biliary Tract Cancer
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Nam AR, Jin MH, Park JE, Bang JH, Oh DY, Bang YJ
- KMID: 2454308
- Cancer Res Treat.
- 2019 Jul;51(3):1167-1179.
- doi: 10.4143/crt.2018.526
PURPOSE: The DNA damage response (DDR) is a multi-complex network of signaling pathways involved in DNA damage repair, cell cycle checkpoints, and apoptosis. In the case of biliary tract cancer... -
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- Does conventional freezing affect sperm DNA fragmentation?
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Le MT, Nguyen TT, Nguyen TT, Nguyen TV, Nguyen TA, Nguyen QH, Cao TN
- KMID: 2452645
- Clin Exp Reprod Med.
- 2019 Jun;46(2):67-75.
- doi: 10.5653/cerm.2019.46.2.67
OBJECTIVE: Sperm cryopreservation has been widely used in assisted reproductive technology, as it offers great potential for the treatment of some types of male infertility. However, cryopreservation may result in... -
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- Clinical significance of cell-free DNA as a prognostic biomarker in patients with diffuse large B-cell lymphoma
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Eskandari , Manoochehrabadi S, Pashaiefar H, Zaimy MA, Ahmadvand
- KMID: 2451011
- Blood Res.
- 2019 Jun;54(2):114-119.
- doi: 10.5045/br.2019.54.2.114
BACKGROUND: Cell-free DNA (cfDNA) has the potential to serve as a non-invasive prognostic biomarker in some types of neoplasia. The investigation of plasma concentration of cfDNA may reveal its use... -
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- Respiratory Syncytial Virus Fusion Protein-encoding DNA Vaccine Is Less Effective in Conferring Protection against Inflammatory Disease than a Virus-like Particle Platform
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Kwon YM, Hwang HS, Lee YT, Kim KH, Lee Y, Kim MC, Lee YN, Quan FS, Moore ML, Kang SM
- KMID: 2450203
- Immune Netw.
- 2019 Jun;19(3):e18.
- doi: 10.4110/in.2019.19.e18
Formalin-inactivated respiratory syncytial virus (RSV) vaccination causes vaccine-enhanced disease (VED) after RSV infection. It is considered that vaccine platforms enabling endogenous synthesis of RSV immunogens would induce favorable immune responses... -
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- Necessity of Guidelines for Research in Forensic Science: DNA Identification
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Jung KW
- KMID: 2448940
- Korean J Leg Med.
- 2019 May;43(2):54-63.
- doi: 10.7580/kjlm.2019.43.2.54
Forensic science is an academic field that utilizes scientific knowledge and the conducting of research in legal procedures. Recently, legal science has been receiving more attention since the use of... -
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- The length of guide RNA and target DNA heteroduplex effects on CRISPR/Cas9 mediated genome editing efficiency in porcine cells
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Lv J, Wu S, Wei R, Li Y, Jin J, Mu Y, Zhang Y, Kong Q, Weng X, Liu Z
- KMID: 2448707
- J Vet Sci.
- 2019 May;20(3):e23.
- doi: 10.4142/jvs.2019.20.e23
The clustered regularly interspaced short palindrome repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system is a versatile genome editing tool with high efficiency. A guide sequence of 20 nucleotides (nt) is commonly... -
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- Cytochrome C Oxidase Subunit 1, Internal Transcribed Spacer 1, Nicotinamide Adenine Dinucleotide Hydrogen Dehydrogenase Subunits 2 and 5 of Clonorchis sinensis Ancient DNA Retrieved from Joseon Dynasty Mummy Specimens
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Hong JH, Oh CS, Chai JY, Seo M, Shin DH
- KMID: 2447038
- J Korean Med Sci.
- 2019 May;34(20):e149.
- doi: 10.3346/jkms.2019.34.e149
We analyzed Clonorchis sinensis ancient DNA (aDNA) acquired from the specimens of the Joseon mummies. The target regions were cytochrome C oxidase subunit 1 (CO1), internal transcribed spacer 1 (ITS1),... -
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- Effect of Sperm DNA Fragmentation on Embryo Quality in Normal Responder Women in In Vitro Fertilization and Intracytoplasmic Sperm Injection
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Kim SM, Kim SK, Jee BC, Kim SH
- KMID: 2443250
- Yonsei Med J.
- 2019 May;60(5):461-466.
- doi: 10.3349/ymj.2019.60.5.461
PURPOSE: To investigate the associations between sperm DNA fragmentation (SDF) and embryo formation rate in normal responder women to in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). MATERIALS AND METHODS: Fifty-three consecutive, fresh... -
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