Ann Geriatr Med Res.
2018 Jun;22(2):98-101. 10.4235/agmr.2018.22.2.98.
Nonsecretory Multiple Myeloma Presenting as Recurrent Vertebral Compression Fractures in an Older Male Patient
- Affiliations
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- 1Department of Pathology, Jeju National University School of Medicine, Jeju, Korea.
- 2Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.
- 3Department of Internal Medicine, Jeju National University Hospital, Jeju, Korea.
- 4Department of Pathology, Gyeongsang National University School of Medicine, Jinju, Korea.
- 5Department of Pathology, Gyeongsang National University Changwon Hospital, Changwon, Korea. shekoh@hanmail.net
- KMID: 2439097
- DOI: http://doi.org/10.4235/agmr.2018.22.2.98
Abstract
- Nonsecretory multiple myeloma is a rare variant of multiple myeloma characterized by the proliferation of clonal plasma cells in the bone marrow. It is difficult to establish an early and accurate diagnosis of nonsecretory multiple myeloma because in nonsecretory myeloma cases, monoclonal immunoglobulin cannot be detected in the serum or urine via electrophoresis. In this report, we describe a case of nonsecretory multiple myeloma presenting as recurrent vertebral compression fractures in a 70-year-old male patient and suggest that nonsecretory multiple myeloma can be included in the differential diagnosis of multiple and recurrent vertebral compression fractures, despite the lack of detectable monoclonal immunoglobulin in the serum or urine by electrophoresis.
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