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Epigenetic and genetic investigation of SOCS-1 gene in patients with multiple myeloma

Tuncel FC, Serin I, Pehlivan S, Oyaci Y, Pehlivan M

Background The suppressor of cytokine signaling-1 (SOCS-1) functions to induce an appropriate immune response and is an essential physiological regulator of interferon signaling. DNA methylation involves adding a methyl group to...
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Spheno-Orbital Plasmacytoma as an Initial Presentation of Multiple Myeloma

Ahn S, Cha SH, Cho WH

Intracranial plasmacytoma is a rare neoplasm and a subtype of malignant plasma cell tumor. Most patients with plasma cell tumors are diagnosed with multiple myeloma, but 5%–10% of patients are...
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Clinical impact of spine magnetic resonance imaging as a valuable prognostic tool for patients with multiple myeloma: a retrospective study

Lee JM, Cho HJ, Moon JH, Sohn SK, Park B, Baek DW

Background: This study investigated the prognostic impact of spine magnetic resonance imaging (MRI) in patients newly diagnosed with multiple myeloma (MM). Methods: We retrospectively evaluated 214 patients who were newly diagnosed...
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Real-world Data-based Adverse Drug Reactions Analysis of Pomalidomide in Patients with Relapsed or Refractory Multiple Myeloma

Ko M, Choi J, Kim S, Kim SH, Cho EJ, Cho YS, Koh YI, Oh JM

Objective: Pomalidomide is a latest-approved immunomodulatory drug used with dexamethasone for patients with relapsed or refractory multiple myeloma (RRMM). However, the real-world safety evidence remains unclear. Thus, we evaluated the...
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Chimeric Antigen Receptor-T Cell Therapy

Byun JM, Yoon SS

Chimeric antigen receptor (CAR) T-cell therapy constitutes a revolutionary advancement in personalized cancer treatment. During this treatment, a patient's own T cells are genetically engineered to express a synthetic receptor...
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Association between Kidney Function, Proteinuria and the Risk of Multiple Myeloma: A Population-Based Retrospective Cohort Study in South Korea

Choi T, Ahn W, Shin DW, Han K, Kim D, Chun S

Purpose While renal impairment is one of the first clinical manifestations of multiple myeloma (MM), declined renal function may conversely be a risk factor for cancers including MM. In this study,...
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Meibomian Gland Dysfunction Associated with Bortezomib in a Multiple Myeloma Patient

Yoon DE, Jun RM, Han KE

Purpose: This study reports a case of meibomian gland dysfunction associated with bortezomib, which is a treatment of choice for multiple myeloma. Case summary: A 59‐year‐old female patient presented to our...
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Single-Center Real-World Experience of Multiple Myeloma in the 21st Century

Cho H, Kim S, Lee K, Kang EH, Park JS, Suh C

Background/Aims: The incidence of multiple myeloma (MM) in Korea is rapidly increasing. The diagnostic criteria of MM have been updated and novel therapeutic agents are available. This study explored the...
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Real-world evidence of levofloxacin prophylaxis in elderly patients with newly diagnosed multiple myeloma who received bortezomib, melphalan, and prednisone regimen

Kim SI, Jung SH, Yhim HY, Jo JC, Song GY, Kim M, Ahn SY, Ahn JS, Yang DH, Kim HJ, Lee JJ

Background Although survival outcomes of multiple myeloma (MM) have improved with the development of new and effective agents, infection remains the major cause of morbidity and mortality. Here, we evaluated the...
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Unstable Pathologic Vertebral Fractures in Multiple Myeloma : Propensity Score Matched Cohort Study between Reconstructive Surgery with Adjuvant Radiotherapy and Radiotherapy Alone

Park HY, Kim YH, Ahn JH, Ha KY, Kim SI, Jung JW

Objective : Although radiotherapy (RT) is recommended for multiple myeloma (MM) involving spine, the treatment of choice between reconstructive surgery with RT and RT alone for pathologic vertebral fractures (PVFs)...
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Structural complexity of the craniofacial trabecular bone in multiple myeloma assessed by fractal analysis

Michels M, Morais-Faria K, Rivera C, Brandão TB, Santos-Silva AR, Oliveira ML

Purpose This study aimed to evaluate the structural complexity of craniofacial trabecular bone in multiple myeloma by fractal analysis of panoramic and lateral skull radiography, and to compare the fractal dimension...
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CT Findings of Granulomatous Pneumocystis jiroveci Pneumonia in a Patient with Multiple Myeloma

Shin SR, Kim TS, Han J

Although the typical CT findings of Pneumocystis jiroveci pneumonia (PJP) include diffuse or multifocal areas of ground-glass opacities in both lungs, it can also rarely manifest as multiple pulmonary nodules....
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Solitary plasmacytoma in the maxillary sinus: 10-year follow-up

Nguyen TTH, Eo MY, Sodnom-Ish B, Cho YJ, Kim SM

Solitary plasmacytoma (SP) is an uncommon form of plasma cell neoplasm occurring intraosseously or in soft tissue and presents as a single mass of monoclonal plasma cells. SP in the...
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Real-world Experience of Improvement in the Survival of Lymphoma and Myeloma Patients with Autologous Stem Cell Transplantation over a 25-year Period

Cho H, Kim S, Lee K, Park JS, Suh C

Background/Aims: The first autologous peripheral blood stem cell transplantation (ASCT) in Korea was performed for a small-cell lung cancer patient at Asan Medical Center (AMC) in 1993. Recently, lymphoma and...
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A Case of Sarcoidosis Associated with Monoclonal Gammopathy

Jeong JH, Park YJ, Hong JS, Lee AY, Lee SH

  • KMID: 2522544
  • Korean J Dermatol.
  • 2021 Nov;59(9):726-727.
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The effect of the response to the coronavirus disease pandemic on treatment outcomes in patients with lymphoma and multiple myeloma

Kang KW, Lee BH, Jeon MJ, Yu ES, Kim DS, Lee SR, Sung HJ, Choi CW, Park Y, Kim BS

Background/Aims: Relatively little data are available on how the response to the coronavirus disease 2019 (COVID-19) pandemic has affected treatment outcomes in patients receiving chemotherapy for lymphoma or multiple myeloma....
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Screening Tests for Early Diagnosis of Multiple Myeloma and Related Plasma Cell Disorders

Kim JS, Yoon SS, Min CK, Lee JJ, Yoon DH, Kim K

Monoclonal gammopathy (MG) encompasses a diverse group of disorders characterized by the secretion of monoclonal immunoglobulins or their light-chain components. The incidence of multiple myeloma (MM) in South Korea is...
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Comprehensive Updates in the Role of Imaging for Multiple Myeloma Management Based on Recent International Guidelines

Lee K, Kim KW, Ko Y, Park HY, Chae EJ, Lee JH, Ryu JS, Chung HW

The diagnostic and treatment methods of multiple myeloma (MM) have been rapidly evolving owing to advances in imaging techniques and new therapeutic agents. Imaging has begun to play an important...
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Oral Phase Dysphagia, the First Manifestation of Systemic Amyloidosis Associated with Multiple Myeloma

Hyun KJ, Kim SH, Kim L, Kim JW

Amyloidosis is a disease in which abnormal proteins called amyloid accumulates in various tissues. In the head and neck area, the larynx is the most common site with the rare...
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Russell Body Lesions of the Colon: Case Report and Literature Review

Tan WK, Smith R, George A, Gibbons A, Shaukat S, Kassam R, Roberts P

Russell bodies (RB) are rare manifestations within the lower gastrointestinal tract. To date, there are only three other reported cases of RB lesions of the colon; two were polyps, and...
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