J Korean Neurosurg Soc.  2001 Dec;30(12):1435-1438.

Nonsecretory Multiple Myeloma with Multiple Spine Fracture

Affiliations
  • 1Department of Neurosurgery, Korea Veterans Hospital, Seoul, Korea.

Abstract

A case of nonsecretory multiple myeloma in a 66 year-old-woman is reported. At first, she complained severe neck pain and radiologic finding showed C2 pathologic fracture. She complained severe low back pain 4 month later and L1 compression fracture was found. The lumbar MRI showed a 1.4cm-sized round enhancing lesion in the body of T12. Bone marrow aspiration biopsy at L1 spine showed a few polymorphous and small nests of mononuclear cell. L1 lamina bone biopsy showed many abnormal plasma cells. Pathologic diagnosis was multiple myeloma. However, plasma electrophoresis and protein immunoelectrophoresis of serum and urine of patient were normal. So, it is a nonecretory multiple myeloma case and the incidence of nonsecretory multiple myeloma is known to about 1% of all multiple myeloma.

Keyword

Multiple myeloma; Nonsecretory; Protein electrophoresis; Protein immunoelectrophoresis; Pathologic fracture

MeSH Terms

Biopsy
Biopsy, Needle
Bone Marrow
Diagnosis
Electrophoresis
Fractures, Compression
Fractures, Spontaneous
Humans
Immunoelectrophoresis
Incidence
Low Back Pain
Magnetic Resonance Imaging
Multiple Myeloma*
Neck Pain
Plasma
Plasma Cells
Spine*
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