Epidemiol Health.  2018;40:e2018023. 10.4178/epih.e2018023.

Korea HIV/AIDS Cohort Study: study design and baseline characteristics

Affiliations
  • 1Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea.
  • 2Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea. jmkim@yuhs.ac
  • 3Division of Infectious Disease, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 4Division of Viral Disease Research, Center for Infectious Diseases Research, Korea, National Institute of Health, Cheongju, Korea.
  • 5Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
  • 6Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
  • 7Center for Infectious Diseases Research, Korea National Institute of Health, Cheongju, Korea.
  • 8Department of Preventive Medicine, Dong-A University College of Medicine, Busan, Korea.
  • 9Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.
  • 10Center for Immunology and Pathology, Cheongju, Korea.
  • 11Department of Nursing, Hanyang University School of Nursing, Seoul, Korea.
  • 12Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
  • 13Department of Infectious Diseases, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

The number of persons infected by HIV/AIDS has consistently increased in Korea since the first case of HIV/AIDS infection in 1985 and reached 15,208 by 2016. About 1,100 new patients with HIV/ AIDS infections have emerged every year since 2013. In Korea, the Korea HIV/AIDS Cohort Study was established for the evidenced-based prevention, treatment, and effective management of patients infected with human immunodeficiency virus (HIV) in December 2006. This study monitored 1,438 patients, who accounted for about 10% of all patients with HIV/AIDS in Korea, for 10 years with the following aims: (1) to develop an administrative system for the establishment of a HIV/AIDS cohort-based study; (2) to standardize methodologies and the case report forms; and (3) to standardize multi-cohort data and develop a data cleaning method. This study aims to monitor at least 1,000 patients (excluding those for whom investigation had been completed) per year (estimated number of patients who can be monitored by January 2018: 939). By December 2016, the sex distribution was 93.3% for men, and 6.7% for women (gender ratio, 13.9:1.0), and 98.9% of all participants were Korean. More than 50.0% of the participants were confirmed as HIV positive after 2006. This study reports competitive, long-term research that aimed to develop policies for the prevention of chronic infectious diseases for patients with HIV. The data collected over the last decade will be used to develop indices for HIV treatment and health promotion.

Keyword

HIV/AIDS; Cohort studies; Sexually transmitted diseases; Communicable diseases

MeSH Terms

Cohort Studies*
Communicable Diseases
Female
Health Promotion
HIV
Humans
Korea*
Male
Methods
Sex Distribution
Sexually Transmitted Diseases
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