Korean J Med.  2018 Dec;93(6):571-574. 10.3904/kjm.2018.93.6.571.

Pneumocystis Pneumonia Developing during Treatment of Recurrent Renal Cell Cancer with Nivolumab

Affiliations
  • 1Division of Hematology and Oncology, Department of Internal Medicine, Pohang Semyeong Christianity Hospital, Pohang, Korea.
  • 2Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. bhumsuk@snu.ac.kr

Abstract

Nivolumab is an immune checkpoint inhibitor approved for the treatment of metastatic cancers. Here, we report the case of a 65-year-old male with recurrent renal cell carcinoma. After six cycles of nivolumab treatment, positron emission tomography/computed tomography (PET/CT) was performed to evaluate the response. PET/CT revealed diffuse ground glass opacities in both lungs. He developed a cough, sputum, chills, and a febrile sense. After bronchoscopic bronchoalveolar lavage, pneumocystis pneumonia was finally diagnosed.

Keyword

Nivolumab; Pneumonia; Pneumocystis pneumonia

MeSH Terms

Aged
Bronchoalveolar Lavage
Carcinoma, Renal Cell*
Chills
Cough
Electrons
Glass
Humans
Lung
Male
Pneumocystis*
Pneumonia
Pneumonia, Pneumocystis*
Positron-Emission Tomography and Computed Tomography
Sputum
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