J Korean Dent Sci.  2018 Dec;11(2):82-85. 10.5856/JKDS.2018.11.2.82.

Diagnosis of Acute Leukemia from Oral Manifestation

• Kang MH
• On D
• Kim JW
• Ryu J

• KMID: 2437345
• DOI: http://doi.org/10.5856/JKDS.2018.11.2.82

Abstract

Leukemia is a hematological malignant disease with various clinical symptoms. Due to the fatal nature of the disease, early detection is important. Oral manifestations include ulcers and gingival enlargement with bleeding. Moreover, myeloid sarcoma or opportunistic infections may also occur. This report introduces a 31-year-old male presenting with generalized gingival enlargement with bleeding and another 81-year-old female with neoplasm on the left retromolar area. Both were diagnosed as acute monocytic leukemia. These cases implicate that gingival enlargement or mucosal lesion in the oral cavity may represent underlying systemic diseases. Related to this, it has to be reminded that making timely diagnosis and referral according to the clinical findings is crucial.

Keyword

Diagnosis; Leukemia; Oral manifestations

MeSH Terms

Adult
Aged, 80 and over
Diagnosis*
Female
Hemorrhage
Humans
Leukemia*
Leukemia, Monocytic, Acute
Male
Mouth
Opportunistic Infections
Oral Manifestations*
Referral and Consultation
Sarcoma, Myeloid
Ulcer