J Korean Child Neurol Soc.  2018 Dec;26(4):246-250. 10.26815/jkcns.2018.26.4.246.

Characteristics of Meningitis with or without Enterovirus

• Cho WJ
• Kwon YR
• Cha BH

• KMID: 2437108
• DOI: http://doi.org/10.26815/jkcns.2018.26.4.246

Abstract

PURPOSE
Meningitis is an acute childhood infection caused by viral or bacterial infection. The purpose of the present study is to analyze the differences between enteroviral meningitis and non-enteroviral aseptic meningitis.
METHODS
From January 2013 to December 2016, we retrospectively reviewed the medical records of a total of 303 aseptic meningitis patients who visited Wonju Severance Christian Hospital. We examined demographics of all patients and analyzed serologic and cerebrospinal fluid tests, clinical symptoms, and outcomes.
RESULTS
Of a total of 303 patients, 197(65.0%) were male, and the most cases occurred from June to November (91.8%). The most common pathogen of meningitis was found to be enterovirus (65.0%). According to the etiology, the enteroviral meningitis group had significantly more headache and enteric symptoms (P=0.0003 and P=0.0013, respectively). Furthermore, the non-enteroviral meningitis group showed pleocytosis in the cerebrospinal fluid and a significantly higher rate of seizure at 1 to 4 years (P=0.0360 and P=0.0002, respectively).
CONCLUSION
In this study, enteroviral meningitis was the most common and the prognosis was good. When compared between two groups, neurological symptoms were frequent in patients with non-enteroviral meningitis in groups 1 to 4 years.

Keyword

Aseptic meningitis; Children; Enterovirus

MeSH Terms

Bacterial Infections
Cerebrospinal Fluid
Child
Demography
Enterovirus*
Gangwon-do
Headache
Humans
Leukocytosis
Male
Medical Records
Meningitis*
Meningitis, Aseptic
Prognosis
Retrospective Studies
Seizures