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Diagnostic Evaluation of the BioFire ® Meningitis/Encephalitis Panel: A Pilot Study Including Febrile Infants Younger than 90 Days

Kim KM, Park JY, Park KU, Sohn YJ, Choi YY, Han MS, Choi EH

Purpose: Rapid detection of etiologic organisms is crucial for initiating appropriate therapy in patients with central nervous system (CNS) infection. This study aimed to evaluate the diagnostic value of the...
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Echovirus-7 Infection in Children with Unusual Severe Manifestation: A Case Report

Pudjiadi AH, Antonjaya U, Myint KS, Alatas FS

We report a rare laboratory-confirmed, clinical case of Echovirus-7 infection in an immunocompetent child with central nervous system and systemic manifestation. Echovirus infection is usually mild, however in this case...
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A Case of Hand-Foot-Mouth Disease Caused by Coxsackievirus A6

Kim HY, Uh JA, Kim JH, Lee JH, Lee SK, Kim MS, Lee UH

  • KMID: 2513441
  • Korean J Dermatol.
  • 2021 Feb;59(2):132-135.
Hand-foot-mouth disease (HFMD) is a viral infection that occurs commonly in children. It is characterized by vesicles with surrounding erythema on the extremities and mouth. Most common pathogens are Coxsackievirus...
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Acute Flaccid Myelitis: Current Status and Diagnostic Challenges

Fang X, Huda R

Acute flaccid myelitis (AFM) is a sudden-onset polio-like neuromuscular disability found commonly in young children. There is an increasing incidence of confirmed AFM cases in the USA and other countries...
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Clinical Differences between Enterovirus and Human Parechovirus in Children and Infants

Rhie S

Purpose: Enteroviruses (EVs) and human parechoviruses (HPeVs) are important pathogens that cause fever in young infants and meningitis in children and have similar clinical symptoms and characteristics. The aim of...
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Enterovirus 71 Encephalitis Responding to Intravenous Immunoglobulin

Lee MA, Lee C, Choi KE, Heo YJ, Na S

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Early Detection and Successful Treatment of Vertically Transmitted Fulminant Enteroviral Infection Associated with Various Forms of Arrhythmia and Severe Hepatitis with Coagulopathy

Lee SR, Ko SY, Yoon SY, Lee YK, Shin SM

Enteroviral infections are common in neonates. One important infection pathway is vertical transmission from an infected mother to her neonate. Here, we report the early detection and successful treatment of...
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Reconsideration of Diagnostic Lumbar Puncture in Childhood Enteroviral Meningitis

Nam JW, Kim TS, Kim JY, Kim JS

PURPOSE: Despite the fact that enteroviral meningitis is the most common cause of meningitis in children with signs of meningeal irritation and has benign course, most clinicians routinely perform an...
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Prevalence of β₂-agonist inhalation for outpatients in a pediatric emergency center during enterovirus D68 epidemic

Zaitsu M, Mizoguchi , Matsuo M, Takayanagi T, Shimada O, Baba T

BACKGROUND: Enterovirus D68 (EV-D68) has been reported to have caused severe bronchial asthma attacks and hospitalization epidemics in Japan in September 2015. OBJECTIVE: To investigate the prevalence of β2-agonist inhalation in...
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Characteristics of Meningitis with or without Enterovirus

Cho WJ, Kwon YR, Cha BH

PURPOSE: Meningitis is an acute childhood infection caused by viral or bacterial infection. The purpose of the present study is to analyze the differences between enteroviral meningitis and non-enteroviral aseptic...
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Clinical Characteristics of Enteroviral Meningitis without Cerebrospinal Fluid Pleocytosis in Children

Kim NR, Ku JK, Lee BL

PURPOSE: The purpose of this study was to investigate the clinical features and laboratory findings of enteroviral meningitis according to the presence of cerebrospinal fluid (CSF) pleocytosis, and to investigate...
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Clinical Characteristics and Epidemiology of Enteroviral Meningitis Compared to Non-Enteroviral Meningitis in Infants under 3 Months of Age

Kim J, Kang HW, Youn YM, Shim SY, Park EA, Cho SJ

OBJECTIVES: To compare the epidemiology, clinical presentation, laboratory findings, seasonality and hospital course of enteroviral meningitis (EM) and non-enteroviral meningitis (NEM) cases in infants under 3 months of age. METHODS: A...
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Neurologic Manifestations according to Serotypes of Enterovirus in Pediatric Inpatient in Incheon

Kim KY, Park JS, Kwon MJ, Kim KS, Kwon YS

PURPOSE: Enterovirus infection in children can manifest various disease and enterovirus have many serotypes. This study was aimed to investigate neurologic manifestations according to serotypes of enterovirus in pediatric inpatients...
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Clinical Features and Neurologic Complications of Pediatric Enteroviral Meningitis

Choi SY, Lee YS, Yu J

PURPOSE: To explore clinical features and neurologic complications of pediatric enteroviral meningitis, and to evaluate risk factors according to the presence of cerebrospinal fluid (CSF) pleocytosis and neurologic complications. METHODS: Retrospective...
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Enterovirus 71 infection and vaccines

Yi EJ, Shin YJ, Kim JH, Kim TG, Chang SY

Hand, foot and mouth disease (HFMD) is a highly contagious viral infection affecting young children during the spring to fall seasons. Recently, serious outbreaks of HFMD were reported frequently in...
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Inhibitory Effects of Norwogonin, Oroxylin A, and Mosloflavone on Enterovirus 71

Choi HJ, Song HH, Lee JS, Ko HJ, Song JH

Severe complications associated with EV71 infections are a common cause of neonatal death. Lack of effective therapeutic agents for these infections underlines the importance of research for the development of...
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Neurologic Manifestations of Enterovirus 71 Infection in Korea

Lee KY, Lee MS, Kim DB

Enterovirus 71 frequently involves the central nervous system and may present with a variety of neurologic manifestations. Here, we aimed to describe the clinical features, magnetic resonance imaging (MRI) findings,...
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Epidemiology and Clinical manifestations of Enterovirus in Pediatric Inpatient in Incheon

Cho BW, Kwon SE, Kwon MJ, Hur MJ, Kim KS, Hong YJ, Kim SK, Kwon YS, Kim DH

PURPOSE: Enterovirus (EV) infection in children can manifest various diseases from asymptomatic infection to nonspecific febrile illness, hand-foot-mouth disease, and aseptic meningitis. This study was aimed to investigate epidemiology and...
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Evaluation of Antiviral Activity of Zanthoxylum Species Against Picornaviruses

Choi HJ

Human rhinoviruses and enteroviruses (family Picornaviridae) infect millions of people worldwide each year, but little is known about effective therapeutical treatment for the infection caused by these viruses. We sought...
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Enterovirus 71 infection and neurological complications

Lee KY

Since the outbreak of the enterovirus 71 (EV71) infection in Malaysia in 1997, large epidemics of EV71 have occurred in the Asia-Pacific region. Many children and infants have died from...
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