Korean J Otorhinolaryngol-Head Neck Surg.  2018 Jun;61(6):308-311. 10.3342/kjorl-hns.2016.17489.

A Case of Hemophilia B Diagnosed after Rhinosinus Surgery in 37 Year-Old Patient

• Kim HD
• Choi IS

• KMID: 2436473
• DOI: http://doi.org/10.3342/kjorl-hns.2016.17489

Abstract

Hemophilia is an X-linked recessive disorder, which is classified into hemophilia A, defined by factor VIII deficiency and hemophilia B, defined by factor IX deficiency. The usual clinical presentation is spontaneous bleeding and prolonged activated partial thromboplastin time in a person without history of a coagulation disorder. The severity of hemophilia describes how serious a problem is and has been defined by a traditional classification into three forms: severe, moderate, mild. Hemophilia has never been reported after a rhinosinus surgery in otorhinolaryngology in Korea, but we encountered a 37-year-old man with hemophilia B who had undergone a rhinosinus surgery. He had no bleeding tendency in the past nor a family history for bleeding. But the patient presented with continuous nasal bleeding for a few days after surgery. We report this case of hemophilia B diagnosed after rhinosinus surgery that was cured with Factor IX replacement therapy with a review of the relevant literature.

Keyword

Endoscopic surgical procedure; Factor IX deficiency; Hemophilia B

MeSH Terms

Adult
Classification
Endoscopy
Epistaxis
Factor IX
Hemophilia A*
Hemophilia B*
Hemorrhage
Humans
Korea
Otolaryngology
Partial Thromboplastin Time
Factor IX