Ann Lab Med.  2012 Nov;32(6):442-444.

The First Korean Case Report of Anti-Gerbich

• Jeon YL
• Park TS
• Cho SY
• Oh SH
• Kim MH
• Kang SY
• Lee WI

Abstract

In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs to the Ge blood group system. The alloantibody was detected in a middle-aged Korean woman who did not have a history of transfusion. Her blood type was B+, and findings from the antibody screening test revealed 1+ reactivity in all panels except the autocontrol. The cross-matching test showed incompatible results with all 5 packed red blood cells. Additional blood type antigen and antibody tests confirmed the anti-Ge alloantibody. While rare, cases of hemolytic transfusion reaction or hemolytic disease in newborns due to anti-Ge have been recently reported in the literature. Therefore, additional further studies on alloantibodies to high-incidence antigens, including anti-Ge, are necessary in the future.

Keyword

Ge; Blood group antigens; Transfusion

MeSH Terms

*ABO Blood-Group System
Asian Continental Ancestry Group
*Blood Group Incompatibility
Blood Grouping and Crossmatching
Female
Glycophorin/immunology
Humans
Isoantibodies/blood/*immunology
Magnetic Resonance Imaging
Middle Aged
Radiculopathy/complications/diagnosis
Republic of Korea
Uterine Cervical Diseases/complications/radiography
ABO Blood-Group System
Glycophorin
Isoantibodies

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