J Neurogastroenterol Motil.  2019 Jan;25(1):123-128. 10.5056/jnm18035.

Functional Chronic Constipation: Rome III Criteria Versus Rome IV Criteria

• Russo M
• Strisciuglio C
• Scarpato E
• Bruzzese D
• Casertano
• Staiano A

• KMID: 2433505
• DOI: http://doi.org/10.5056/jnm18035

Abstract

BACKGROUND/AIMS
Functional constipation (FC) is aa frequent functional gastrointestinal disorder, diagnosed according to the Rome criteria. In this study, we compared Rome III and Rome IV criteria for the diagnosis of FC, and determined the prevalence of FC according to these criteria.
METHODS
Consecutive children between infancy and 17 years old were recruited for the study, excluding those with a known organic gastrointestinal disease. A prospective longitudinal design has beenused. For the diagnosis of FC, questionnaires on Pediatric Gastrointestinal Symptoms (QPGS) based on the Rome III and Rome IV criteria (QPGS-RIII and QPGS-RIV) were used. The agreement between these 2 questionnaires was measured by Cohen's kappa coefficient.
RESULTS
Two hundred fourteen children (mean age, 77.4 ± 59.5 months; 103 males) were screened. There was no statistically significant difference in the prevalence of FC evaluated using the QPGS-Rome IV vs the QPGS-Rome III in the overall sample (39/214 [18.2%] vs 37/214 [17.3.0%]; P = 0.831) as well as in any of the groups. The Cohen's kappa test showed a good agreement between the 2 criteria (κ = 0.65; 95% CI, 0.51 to 0.78).
CONCLUSION
Our study demonstrates that the new Rome IV criteria have a good agreement with the Rome III criteria for the diagnosis of FC, without an increase in the number of potential diagnoses, despite the reduction in the duration of the symptoms. This conclusion is important in the management of childhood FC, since a late diagnosis negatively affects the prognosis.

Keyword

Functional constipation; Pediatric; Questionnaires

MeSH Terms

Child
Constipation*
Delayed Diagnosis
Diagnosis
Gastrointestinal Diseases
Humans
Prevalence
Prognosis
Prospective Studies