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Does the Oral-Anal Transit Test Correlate with Colonic Manometry Findings in Children with Refractory Constipation?

Dranove J, Fleishman , Reddy S, Teich S

PURPOSE: The Oral-anal Transit Test (OTT) is a simple method of obtaining information about colonic transit. We aim to assess the correlation of OTT with the neuromuscular integrity of the...
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A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation

Mori S, Tomita T, Fujimura K, Asano H, Ogawa T, Yamasaki T, Kondo T, Kono T, Tozawa K, Oshima T, Fukui H, Kimura T, Watari J, Miwa H

  • KMID: 2460486
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):563-575.
  • doi: 10.5056/jnm18194
BACKGROUND/AIMS: Magnesium oxide (MgO) has been frequently used as a treatment for chronic constipation (CC) since the 1980s in Japan. The aim of this study is to evaluate its therapeutic...
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Metabolomics approach to serum biomarker for laxative effects of red Liriope platyphylla in loperamide-induced constipation of SD rats

Kim JE, Lee YJ, Ryu SH, Park JW, Kang MJ, Choi HJ, Bae SJ, Choi Y, Kang HG, Kim KB, Kim S, Lim Y, Hwang DY

Red Liriope platyphylla (RLP) is a known herbal medicine used in the treatment of some chronic diseases including constipation, neurodegenerative disorders, diabetes and obesity. To determine and characterize putative biomarkers...
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Modulatory Effects of Gut Microbiota on Constipation: The Commercial Beverage Yakult Shapes Stool Consistency

Chen M, Ye X, Shen D, Ma C

  • KMID: 2454647
  • J Neurogastroenterol Motil.
  • 2019 Jul;25(3):475-477.
  • doi: 10.5056/jnm19048
No abstract available.
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Nationwide Survey for Application of ROME IV Criteria and Clinical Practice for Functional Constipation in Children

Jang HJ, Chung JY, Seo JH, Moon JS, Choe BH, Shim JO

BACKGROUND: This study aimed to investigate the awareness and application of ROME IV criteria for functional constipation (FC) in real-world practices and assessed differences between pediatric gastroenterologists (PGs) and general...
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The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study

Benninga M, MENA Infant Constipation Study Group, Vandenplas Y

PURPOSE: To compare the effectiveness of the magnesium (Mg)-enriched formula vs. control formula in constipated infants. METHODS: An open-label, interventional, and the comparator-controlled study was conducted to evaluate the effectiveness of...
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Opioid-induced constipation: a narrative review of therapeutic options in clinical management

Lang-Illievich K, Bornemann-Cimenti H

Pain therapy often entails gastrointestinal adverse events. While opioids are effective drugs for pain relief, the incidence of opioid-induced constipation (OIC) varies greatly from 15% to as high as 81%....
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Effect of Mizagliflozin on Postprandial Plasma Glucose in Patients With Functional Constipation

Fukudo S, Kaku K

  • KMID: 2449104
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):332-333.
  • doi: 10.5056/jnm19010
No abstract available.
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High Prevalence of Slow Transit Constipation in Patients With Gastroparesis

Zikos TA, Kamal AN, Neshatian , Triadafilopoulos G, Clarke JO, Nandwani M, Nguyen LA

  • KMID: 2449099
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):267-275.
  • doi: 10.5056/jnm18206
BACKGROUND/AIMS: Current evidence suggests the presence of motility or functional abnormalities in one area of the gastrointestinal tract increases the likelihood of abnormalities in others. However, the relationship of gastroparesis...
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High-resolution Anorectal Manometry in the Diagnosis of Functional Defecation Disorder in Patients With Functional Constipation: A Retrospective Cohort Study

Zhao Y, Ren X, Qiao W, Dong L, He S, Yin Y

  • KMID: 2449097
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):250-257.
  • doi: 10.5056/jnm18032
BACKGROUND/AIMS: High-resolution anorectal manometry (HRAM) has been considered a first-line diagnostic tool for functional defecation disorder. However, clinical studies on HRAM used in constipation patients are very limited and few...
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Transabdominal Functional Magnetic Stimulation for the Treatment of Constipation in Brain-Injured Patients: A Randomized Controlled Trial

Yun YC, Yoon YS, Kim ES, Lee YJ, Lee JG, Jo WJ, Lee KJ

OBJECTIVE: To investigate the effects of the transabdominal functional magnetic stimulation (A-FMS) for constipation in stroke or brain-injured patients. METHODS: Twenty-four brain-injured patients (11 males and 13 females; median age, 65...
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Chronic Functional Constipation

Shin JE, Park KS, Nam K

Constipation is a common functional problem of the digestive system and may occur secondary to diet, drugs, endocrine diseases, metabolic diseases, neurological diseases, psychiatric disorders, or gastrointestinal obstruction. When there...
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Success and Complication Rates After Sacral Neuromodulation for Fecal Incontinence and Constipation: A Single-center Follow-up Study

Widmann B, Galata C, Warschkow , Beutner U, Ögredici , Hetzer FH, Schmied BM, Post S, Marti L

  • KMID: 2433509
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):159-170.
  • doi: 10.5056/jnm17106
BACKGROUND/AIMS: The aim of this study was to evaluate the sustainability of sacral neuromodulation (SNM) success in patients with fecal incontinence (FI) and/or constipation. METHODS: This is a retrospective analysis of...
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Differential Effects of Lactobacillus casei Strain Shirota on Patients With Constipation Regarding Stool Consistency in China

Chen S, Ou Y, Zhao L, Li Y, Qiao Z, Hao Y, Ren F

  • KMID: 2433508
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):148-158.
  • doi: 10.5056/jnm17085
BACKGROUND/AIMS: Probiotics are expected to confer benefits on patients with constipation, but how probiotics act on constipated patients with variable stool consistencies remains unclear. We investigated the effect of Lactobacillus...
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Pelvic Floor Symptom Related Distress in Chronic Constipation Correlates With a Diagnosis of Irritable Bowel Syndrome With Constipation and Constipation Severity but Not Pelvic Floor Dyssynergia

Singh P, Seo Y, Ballou S, Ludwig A, Hirsch W, Rangan V, Iturrino J, Lembo A, Nee JW

  • KMID: 2433506
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):129-136.
  • doi: 10.5056/jnm17139
BACKGROUND/AIMS: Although symptoms related to the pelvic floor, such as pelvic organ prolapse (POP) and lower urinary tract symptoms (LUTS), are common in patients with chronic constipation (CC), its impact...
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Functional Chronic Constipation: Rome III Criteria Versus Rome IV Criteria

Russo M, Strisciuglio C, Scarpato E, Bruzzese D, Casertano , Staiano A

  • KMID: 2433505
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):123-128.
  • doi: 10.5056/jnm18035
BACKGROUND/AIMS: Functional constipation (FC) is aa frequent functional gastrointestinal disorder, diagnosed according to the Rome criteria. In this study, we compared Rome III and Rome IV criteria for the diagnosis...
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Understanding the Changes in Diagnostic Criteria for Functional Constipation in Pediatric Patients: From Rome III to Rome IV

Lee YJ, Park KS

  • KMID: 2433492
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):3-5.
  • doi: 10.5056/jnm18199
No abstract available.
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Regulation of gastrointestinal hormones during laxative activity of gallotannin-enriched extract isolated from Galla Rhois in loperamide-induced constipation of SD rats

Kim JE, Kang MJ, Choi JY, Park JJ, Lee MR, Song BR, Kim HR, Park JW, Choi HJ, Bae SJ, Hwang DY

Regulation of gastrointestinal hormones have been reported in animal models for constipation undergoing laxative therapy when administered herbal products. We undertook to investigate whether the laxative activity of gallotannin-enriched extracts...
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Medical Professionals' Review of YouTube Videos Pertaining to Exercises for the Constipation Relief

Lee TH, Kim SE, Park KS, Shin JE, Park SY, Ryu HS, Kim JW, Lee YJ, Cho YS, Park S, Constipation Research Group of The Korean Society of Neurogastroenterology and Motility

BACKGROUND/AIMS: The primary aims of this study were to evaluate the content quality of YouTube videos on exercises to help relieve constipation and to assess whether the video source, exercise...
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Aging Decreases the Density of Colonic Interstitial Cells of Cajal Associated With Constipation in Rats

Xiao J

  • KMID: 2413110
  • J Neurogastroenterol Motil.
  • 2018 Apr;24(2):326-328.
  • doi: 10.5056/jnm18016
No abstract available.
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