Ann Dermatol.  2019 Feb;31(1):108-110. 10.5021/ad.2019.31.1.108.

Benign Atypical Intralymphatic CD30+ T-Cell Proliferation: A Case Report and Literature Review

• Jang NR
• Kim MK
• Shin DH
• Gu MJ

• KMID: 2430816
• DOI: http://doi.org/10.5021/ad.2019.31.1.108

Abstract

No abstract available.

MeSH Terms

T-Lymphocytes*

Figure

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  Fig. 1 (A) A well demarcated ulcer was on penile shaft. (B) Two month later, the lesion was regressed without any treatment.

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  Fig. 2 (A) The epidermis showed ulceration and superficial dermis contained thin-walled dilated lymphatic vessels with atypical lymphoid cells (H&E, ×4). (B) Intralymphatic atypical lymphoid cells infiltration (H&E, ×200). The atypical cells express CD3 (C, ×400) and CD30 (D, ×400). The lymphatic spaces are highlighted by D2-40 (E, ×400).

Reference

1. Kempf W, Keller K, John H, Dommann-Scherrer C. Benign atypical intravascular CD30+ T-cell proliferation: a recently described reactive lymphoproliferative process and simulator of intravascular lymphoma: report of a case associated with lichen sclerosus and review of the literature. Am J Clin Pathol. 2014; 142:694–699.

2. Riveiro-Falkenbach E, Fernández-Figueras MT, Rodríguez-Peralto JL. Benign atypical intravascular CD30(+) T-cell proliferation: a reactive condition mimicking intravascular lymphoma. Am J Dermatopathol. 2013; 35:143–150.

3. Samols MA, Su A, Ra S, Cappel MA, Louissant A Jr, Knudson RA, et al. Intralymphatic cutaneous anaplastic large cell lymphoma/lymphomatoid papulosis: expanding the spectrum of CD30-positive lymphoproliferative disorders. Am J Surg Pathol. 2014; 38:1203–1211.

4. Nguyen GH, Yassin AH, Magro CM. Unusual variants of intravascular malignant hematopoietic neoplasms: a report of 4 cases and review of the literature. Am J Dermatopathol. 2015; 37:360–367.

5. Calamaro P, Cerroni L. Intralymphatic proliferation of T-cell lymphoid blasts in the setting of hidradenitis suppurativa. Am J Dermatopathol. 2016; 38:536–540.