Korean J Dermatol.  2000 Mar;38(3):417-420.

A Case of Primary Cutaneous CD30-Positive Lymphoproliferative Disorder: Borderline case

Affiliations
  • 1Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
  • 2Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.

Abstract

Primary cutaneous CD30-positive large cell lymphoma and lymphomatoid papulosis; both entities are characterized by CD30-positive large atypical cells predominantly of T cell origin. We report a borderline case between CD30-positive large cell lymphoma and lymphomatoid papulosis in a 57-year-old woman presenting as a spontaneous disappearing and recurrent solitary erosive nodule on the right upper eyelid. Histopathological findings of two biopsies from each lesion showed mixed CD30-positive large atypical cells, many eosinophils and neutrophils histologically. The nodule disappeared after chemotherapy and subsequent radiotherapy. She is well without recurrence for a follow-up of 9 months.

Keyword

Primary cutaneous CD30-positive lymphoproliferative disorder

MeSH Terms

Biopsy
Drug Therapy
Eosinophils
Eyelids
Female
Follow-Up Studies
Humans
Lymphoma
Lymphomatoid Papulosis
Lymphoproliferative Disorders*
Middle Aged
Neutrophils
Radiotherapy
Recurrence
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