Korean J Dermatol.
2008 Dec;46(12):1615-1618.
A Case of Atypical CD30+ Lymphocytic Hyperplasia Following Tick Bite
- Affiliations
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- 1Department of Dermatology, College of Medicine, Eulji University, Seoul, Korea. kpark@eulji.ac.kr
Abstract
- Since the discovery of the CD30 molecule, its expression has been considered a reliable marker for CD30+ lymphomas, including lymphomatoid papulosis, primary cutaneous anaplastic large cell lymphoma and borderline cases. However, CD30+ cells can be observed in Hodgkin's lymphoma, as well as in T-cell and B-cell lymphomas or NK cell lymphomas. Furthermore, it can also be found in reactive inflammatory disorders or in non-lymphoid neoplasms. It is very important to differentiate between lymphomas and reactive inflammatory disorders using a combination of clinical, histological, phenotypic and molecular analyses. We report a case of atypical CD30+ lymphocytic hyperplasia in a 57-year-old man following tick bite.
