Korean J Radiol.  2017 Apr;18(2):378-382. 10.3348/kjr.2017.18.2.378.

Magnetic Resonance Imaging Findings of Mumps Meningoencephalitis with Bilateral Hippocampal Lesions without Preceding Acute Parotitis: A Case Report

• Woo AR
• Lee HY
• Lim MK
• Kang YH
• Cho SG
• Choi SH
• Baek JH

• KMID: 2427950
• DOI: http://doi.org/10.3348/kjr.2017.18.2.378

Abstract

Meningitis is a common central nervous system (CNS) complication of the mumps, a viral infection, but encephalitis and meningoencephalitis are less common in mumps. We describe magnetic resonance imaging findings of acute mumps meningoencephalitis in a 32-year-old male who showed bilateral hippocampal lesions without preceding parotitis. Although it is rare, hippocampal involvement should be considered a CNS complication of mumps infection.

Keyword

Mumps; Encephalitis; Meningoencephalitis; Hippocampus; Brain; Magnetic resonance imaging

MeSH Terms

Acute Disease
Adult
Hippocampus/*diagnostic imaging
Humans
*Magnetic Resonance Imaging
Male
Meningoencephalitis/*diagnosis/diagnostic imaging
Mumps/*diagnosis
Parotitis/diagnosis

Figure

• 

  Fig. 1 Brain MRI taken 7 days after seizure onset in 32-year-old male patient. Axial T2-weighted image (A) and diffusion-weighted image (B) showing high signal intensities in bilateral hippocampi (arrows) but no significant abnormality on corresponding apparent diffusion coefficient map (C). Axial post-contrast T1-weighted image (D) showing diffuse leptomeningeal enhancement and no enhancement of bilateral hippocampal lesions.

• 

  Fig. 2 Follow-up brain MRI at day 20 after seizure onset. Axial T2-weighted (A) and diffusion-weighted (B) images showing bilateral hippocampal lesions had diminished and post-contrast axial T1-weighted image (C) showing disappearance of leptomeningeal enhancement (C).

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